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Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER VI • EXAMINATION WINTER • 2016
Subject Code: 260005 Date: 25-10-2016
Subject Name: Clinical Pharmacy-I
Time: 02:30 pm 05:30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Write causes, sign symptoms, mechanisms of arrhythmia and discuss how class anti-arrhythmic drugs manage arrhythmia
06

Discuss risk factors and pathophysiology of Alzheimer diseases
05

Write sources, mechanism of toxicity, signs and symptoms, diagnosis and treatment of chronic Arsenic poisoning
05
Q.2

Describe criteria for Therapeutic Drug Monitoring and Immunological methods used for TDM with suitable examples
06

Discuss detail pathophysiology and management of Parkinsonism
05

Discuss on self medication and nonprescription drug usage
05
Q.3

Define rational use of medicines, give examples of the irrational use of medicines and discuss Pharmacist's role in promoting rational use of medicines
06

Write how to perform initial evaluation of hypertensive patients and explain hypertensive crises: emergencies and urgencies
05

Write short note on Pain and Migraine
05
Q.4

Explain the roll and responsibility of clinical pharmacist as a member of health care team
06

Explain metabolic and systemic consequences of chronic kidney disease
05

Explain pharmacokinetic differences in pediatric population
05
Q.5

Define laboratory test abnormalities and write its general principles and give detail of serum proteins tests
06

Explain pathophysiology and management of stroke
05

Discuss FDA pregnancy categories with suitable examples.
05
Q. 6

Discuss the medication related problems in geriatric patients and reasons for high frequencies of adverse drug reactions in the elderly
06

Write detail Interpretation of blood urea nitrogen laboratory tests and their effect on drug therapy decisions.
05

Discuss etiology, clinical presentation diagnosis and treatment of megaloblastic anemias
05
Q.7

Define poison and write mechanism of action, signs symptoms,
06
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diagnosis and management of Organophosphorus poisoning

Explain the clinical pharmacist roll in improving patient compliance and providing patient counseling
05

Discuss etiology, clinical presentation, diagnosis and therapeutic plan for Thrombosis
05