M.Sc. DEGREE EXAMINATION, APRIL 2016
Bio Technology
BIOINFORMATICS
(2013 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 2 20)
Answer all questions.
All questions carry equal marks.
1. Define Bioinformatics.
2. Name any two software used for the visualization of
proteins.
3. Name the algorithms used for global and local alignment.
4. Write about the types of phylogenetic tree?
5. Name any two tools used for protein secondary structure
prediction.
6. What is motif?
7. What is electropherogram?
8. Define proteomics.
9. Define molecular modelling.
10. What is rational drug design?
Sub. Code
501301
RW-10969
2
Wk 9
Part B 5 25)
Answer all questions.
All questions carry equal marks.
11. Expand and explain briefly about EMBOSS
Or
Discuss briefly about Open source software.
12. What is Pairwise alignment. Explain briefly.
Or
What is multiple Sequence alignment? Explain
briefly.
13. Explain about protein secondary Structure
prediction.
Or
Describe RNA Structure analysis.
14. Define Contig Explain about contig assembly.
Or
Describe about computational proteomics.
15. Explain briefly about virtual screening.
Or
Explain briefly about molecular docking.
Part C 10 30)
Answer any three of the following.
16. Describe in detail about Biological databases.
17. What is sequence alignment? Explain in detail.
RW-10969
3
Wk 9
18. Discuss about protein tertiary structure prediction
methods.
19. Explain in detail about microarray and q-PCR data
analysis.
20. Explain in detail about
Ligand -based drug design.
Structure -based drug design.