THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
(LO 2018) MARCH 2019 Sub. Code: 2018
B.PHARM. DEGREE EXAMINATION
PCI Regulation SEMESTER II
PAPER III BIOCHEMISTRY
Q.P. Code: 562018
Time: Three hours Maximum: 75 Marks
I. Elaborate on: Answer any TWO questions. x 10 20)
1. Describe protein synthesis and its inhibitors.
2. Explain De novo synthesis of fatty acids.
3. Discuss about gluconeogenesis.
II. Write notes on: Answer any SEVEN questions. x 5 35)
1. Enumerate the IUB classification of enzymes.
2. Summarise glycogenolysis.
3. Outline the biosynthesis of pyrimidine nucleotides.
4. Describe catabolism of aminoacids.
5. Briefly explain organization of mammalian genome.
6. Explain Jaundice and its types.
7. Describe the relationship between free energy, enthalpy and entropy.
8. Explain Alkaptonuria and Phenylketonuria.
9. Define and classify lipids.
III. Short answers on: Answer ALL questions. (10 x 2 20)
1. Define enthalpy and entropy.
2. Write the energetic for glycolysis pathway.
3. Enlist uncouplers in oxidative phosphorylation.
4. What is fatty liver?
5. Write the conversion of phenylalanine to tyrosine.
6. What is hyperuricemia?
7. What is transcription?
8. What is enzyme induction and repression?
9. What is ketoacidosis?
10. Name essential aminoacids.