Exam Details
| Subject | modern pharmaceutical analysis | |
| Paper | ||
| Exam / Course | m.pharm | |
| Department | ||
| Organization | Gujarat Technological University | |
| Position | ||
| Exam Date | January, 2019 | |
| City, State | gujarat, ahmedabad |
Question Paper
Page 1 of 2
Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
M.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: MAT101T Date: 01/01/2019
Subject Name: Modern Pharmaceutical Analytical Techniques
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Enumerate methods used for estimation of multicomponent system. Explain Virordt's method
06
Explain terms: (any five)
Chromophore ii) Auxochrome iii) Hypsochromic shift
iv) Red shift Quenching vi) Iso-electric focusing
05
Write applications of UV spectroscopy. Give difference between Single-beam and Double beam UV spectrophotometer.
05
Q.2
Write short note on detectors used in IR spectroscopy.
06
Write short note on Hollow Cathode Lamp.
Or
What is ion-selective electrode? Write the basic principle of Potentiometer.
05
Enumerate the mass analyzer and explain any two in detail.
05
Q.3
What is Chemical shift? Write factors affecting on chemical shift.
06
Write short note on: (any two)
Spin-spin coupling in PMR ii) Coupling constant
iii) Difference between Atomic Absorption and Atomic Emission Spectroscopy.
05
Write the applications, advantages and disadvantages of NMR spectroscopy.
05
Q.4
Enumerate ionization sources of Mass spectroscopy.
Describe Gas phase ionization.
06
Write applications of Mass spectroscopy.
05
Write short note on Mass detectors.
05
Q.5
What is Chromatography? Enumerate different types of chromatography techniques. Write the principle of ion-exchange chromatography.
06
Give difference between:
Guard column and Analytical column
Normal phase and Reverse Phase chromatography.
05
Page 2 of 2
Write short note on stationary phase and mobile phase of Gas chromatography.
05
Q. 6
Write short note on Affinity chromatography.
06
What is electrophoresis? Give different types of electrophoresis. Explain any one in detail.
05
Write advantages and disadvantages of Paper, Capillary and Zone electrophoresis.
05
Q.7
Write different types of crystals. Give applications of X-ray diffraction.
06
How to produce X-ray? Draw labelled diagram of X-ray tube.
05
Answer the following:
What is tandem mass spectroscopy?
Or
Write principle of thin layer chromatography.
ii) What is molecular vibration?
iii) Write the factors affecting on thermal analysis.
05
Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
M.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: MAT101T Date: 01/01/2019
Subject Name: Modern Pharmaceutical Analytical Techniques
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Enumerate methods used for estimation of multicomponent system. Explain Virordt's method
06
Explain terms: (any five)
Chromophore ii) Auxochrome iii) Hypsochromic shift
iv) Red shift Quenching vi) Iso-electric focusing
05
Write applications of UV spectroscopy. Give difference between Single-beam and Double beam UV spectrophotometer.
05
Q.2
Write short note on detectors used in IR spectroscopy.
06
Write short note on Hollow Cathode Lamp.
Or
What is ion-selective electrode? Write the basic principle of Potentiometer.
05
Enumerate the mass analyzer and explain any two in detail.
05
Q.3
What is Chemical shift? Write factors affecting on chemical shift.
06
Write short note on: (any two)
Spin-spin coupling in PMR ii) Coupling constant
iii) Difference between Atomic Absorption and Atomic Emission Spectroscopy.
05
Write the applications, advantages and disadvantages of NMR spectroscopy.
05
Q.4
Enumerate ionization sources of Mass spectroscopy.
Describe Gas phase ionization.
06
Write applications of Mass spectroscopy.
05
Write short note on Mass detectors.
05
Q.5
What is Chromatography? Enumerate different types of chromatography techniques. Write the principle of ion-exchange chromatography.
06
Give difference between:
Guard column and Analytical column
Normal phase and Reverse Phase chromatography.
05
Page 2 of 2
Write short note on stationary phase and mobile phase of Gas chromatography.
05
Q. 6
Write short note on Affinity chromatography.
06
What is electrophoresis? Give different types of electrophoresis. Explain any one in detail.
05
Write advantages and disadvantages of Paper, Capillary and Zone electrophoresis.
05
Q.7
Write different types of crystals. Give applications of X-ray diffraction.
06
How to produce X-ray? Draw labelled diagram of X-ray tube.
05
Answer the following:
What is tandem mass spectroscopy?
Or
Write principle of thin layer chromatography.
ii) What is molecular vibration?
iii) Write the factors affecting on thermal analysis.
05
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Subjects
- advanced medicinal chemistry
- advanced organic chemistry-i
- advanced organic chemistry-ii
- advanced pharmacology ii
- advanced pharmacology-i
- advances in drug delivery system
- advances in pharmacology
- applied pharmacotherapeutics - ii
- applied pharmacotherapeutics-i
- audits and regulatory compliance
- biological evaluations & clinical research
- cellular and molecular pharmacology
- clinical and hospital pharmacy
- clinical pharmacy practice
- clinical research and pharmacy practice
- clinical research and regulatory affairs
- clinical research regulations
- cosmetic and cosmeceuticals
- documentation and regulatory writing
- drug design and discovery
- drug regulation and regulatory authority
- experimental design and patents
- global regulatory requirements
- gmp, glp and validation
- good manufacturing and good laboratory practice
- good manufacturing practice and process validation
- good regulatory practices
- hazards and safety management
- industrial pharmacy practice
- modern analytical techniques
- modern pharmaceutical analysis
- novel drug delivery system part-i
- novel drug delivery system-ii
- pharm. management -ii
- pharmaceutical analysis ii
- pharmaceutical and cosmetic analysis
- pharmaceutical formulation and development
- pharmaceutical formulation development and biopharmceutics
- pharmaceutical manufacturing technology
- pharmaceutical production management & technology
- pharmaceutical regulatory affairs
- pharmacological and toxicological screening methods-i
- pharmacological and toxicological screening methods-ii
- pharmacometrics and methods of biological evaluation of drugs
- pharmacotherapeutics
- principles of biopharmaceutics& pharmacokinetics
- product development and technology transfer
- quality control & quality assurance
- quality control and quality assurance
- quality management system
- regulatory affairs - i
- regulatory affairs and new drug applications
- regulatory aspects of hebbal and biologicals
- research methodology
- validation and product development