Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
M.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: MCP103T Date: 05/01/2019
Subject Name: Clinical Toxicology Pharmacovigilance
Time :10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Role of clinical pharmacist in reporting, evaluation, and management of ADR
06

Explain in detail the clinical symptoms and management of acute poisoning of
Salicylates.
05

Explain in detail carbamate poisoning.
05
Q.2

Write a note on the general principles in the management of heavy metals poisoning.
06

Write the signs and symptoms and treatment of opioid dependence.
05

Discuss the need for medicine information services.
05
Q.3

Write a note on gut decontamination.
06

Write a brief note on toxicokinetics.
05

Discuss the factors and approaches to be considered for the evaluation of causality assessment.
05
Q.4

Write the clinical manifestations and management of chronic mercury poisoning.
06

Discuss symptoms, and management of food poisoning.
05

Mention the clinical symptoms and specific antidote for pyrethroids poisoning.
05
Q.5

Explain in detail about the general principles involved in the management of poisoning.
06

Clinical symptoms and management of radiations poisoning.
05

Discuss the toxicity of benzodiazepines and its treatment.
05
Q. 6

What are the symptoms, signs, and treatment of Organophosphorus compound poisoning?
06

Clinical features of acute methanol poisoning and its treatment.
05

Discuss various methods and importance of elimination enhancement in the treatment of poisoning.
05
Q.7

Write the requirements for establishment of drug information center.
06

Discuss organization and functions of poison information centre.
05

List down the signs and symptoms to detect poisoning cases with examples.
05