Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
PHARM.D YEAR EXAMINATION -WINTER 2018
Subject Code: 828802 Date: 22/11/2018
Subject Name: Pharmaceutical Microbiology
Time: 02.30 P.M. TO 5.30 P.M. Total Marks: 70
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

What is microbiology? Write about significance of microbiology in pharmaceutical field.
06

Write a note on cell wall of gram negative bacteria.
04

Write in short about fungi and spirochetes.
04
Q.2

Discuss methods for counting of total and viable bacteria.
06

Explain the term F-value D-value.
04

How will you perform sterility testing of ciprofloxacin eye drops 10 ml with batch size 10000 containers?
04
Q.3

Write a note on gaseous sterilization.
06

Explain in short about different types of microorganisms.
04

Give the ideal properties of disinfectants. Explain mechanism of action of alcohol as disinfectant.
04
Q.4

Differentiate between bacteria, viruses and rickettsia.
06

Describe the method of evaluation of disinfectants and interpretation of its results.
04

Classify bacteria.
04
Q.5

Write a note on nutritional requirement, growth and cultivation of bacteria.
06

Write about phagocytosis and acquired immunity.
04

Describe Schick's test and western blot test.
04
Q. 6

Explain the terms Infection, Immunity and Microbial resistance with suitable example.
06

Write a note on Meningitis Tuberculosis.
04

Describe the microbiological assay of Penicillin.
04
Q.7

Classify methods of sterilization. Explain any one physical method of sterilization.
06

Describe significance of toxoids in active immunity.
04

Write a note on cell wall of gram positive bacteria.
04