Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
PHARM.D YEAR EXAMINATION -WINTER 2018
Subject Code:828801 Date: 19/11/2018
Subject Name: Pathophysiology
Time:02.30 P.M. TO 5.30 P.M. Total Marks: 70
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Define and classify cellular adaptations. Write a note on atrophy.
06

Write a note on pathogenesis of COPD.
04

Discuss differences between malignant and benign tumors.
04
Q.2

Define acute inflammation. Write role of chemical mediators in inflammation.
06

Write mechanisms of allograft rejection.
04

Write a note on acute renal failure.
04
Q.3

Define thrombosis. Discuss etiological factors and pathogenesis of thrombosis.
06

Explain life cycle of malarial parasite.
04

Enlist various inflammatory cells and discuss role of any two cells in inflammation.
04
Q.4

Define and classify anemia. Write symptoms and pathophysiology of Iron deficiency anemia.
06

Write symptoms and pathogenesis of depression.
04

Enumerate various shocks. Write a note on anaphylactic shock.
04
Q.5

Define radiation injury. Explain mechanisms involved in radiation induced damage to the DNA of cell.
06

Write differences between ulcerative colitis and crohn's disease.
04

Discuss etiology and general biology of tumor.
04
Q. 6

Discuss risk factors, pathogenesis and complications of type-1 diabetes mellitus.
06

Write a note on Amyloidosis.
04

Discuss in detail toxic effects of SO2.
04
Q.7

Classify hypersensitivity reactions. Discuss cell mediated hypersensitivity reaction in detail.
06

Write etiology and pathogenesis of AIDS.
04

Discuss factors affecting healing of wound.
04