Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
D.Pharm 1st Year • EXAMINATION WINTER -2018
Subject Code: Pharmaceutics I Date:19/11/2018
Subject Name: 410001
Time: 10:30A.M. TO 1:30 P.M Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Define tablets. Give advantage and disadvantage of tablets dosage form.
Enumerate various tablet excipients with suitable examples.
06

Define percolation. Discuss various steps involved in percolation process.
05

Define capsule. Give its advantage disadvantage. Write composition of hard
gelatin capsule shell and soft gelatin capsule shell.
05
Q.2

Give the objectives of size reduction. Discuss the factors affecting size reduction process.
06

Define Filteration and discuss various factors affecting rate of Filteration.
05

Discuss evaluation of tablets as per IP.
05
Q.3

Discuss the various factors affecting the rate of evaporation. Write a note on evaporating stills.
06

Define size reduction. Discuss principle, working, applications, advantages and disadvantages of Ball mill with suitable diagram.
05

Define and classify dosage form.
05
Q.4

Enumerate various methods of size separation. Explain construction and
working of cyclone separator.
06

Write a note on Planetary Mixer
05

Write a note on Indian Pharmacopoeia.
05
Q.5

Define Sterilization. Classify different methods of sterilization. Write briefly on Moist heat sterilization.
06

Enlist different types of distillation process. Briefly describe steam distillation.
05

Write a note on Colloidal mill.
05
Q. 6

Differentiate followings. (Any Two)
Syrup IP and Syrup USP
Active immunity and Passive immunity
Evaporation and Distillation
06

Define Size separation. Write about elutriation method for size separation.
05

Define Isotonicity. How to adjust isotonicity in brief.
05
Q.7

How many parts of 34% and 25% alcohol to be mixed together so
as to give 40% alcohol.
ii) Multiply 5 pt, 7 fl. Oz and 4 fl. dr by 4.
06

Write about sugar coating of tablet.
05

Write a note on freeze drying.
05