Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
PHARM.D YEAR-3 EXAMINATION SUMMER-2019
Subject Code: 838801 Date: 06/05/2019
Subject Name: Pharmacology-II
Time: 02:30 PM TO 05:30 PM Total Marks: 70
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks
Q.1 Discuss the advantages and disadvantages of combination of sulphonamide 06
with trimetoprem.
Explain the pharmacology of furosemide. 04
Describe the toxicities of aminoglycoside antibiotics. 04
Q.2 Define and classify anticoagulants. Write the mechanism of action of 06
Warfarin.
Write a note on anticancer antibiotics. 04
Discuss the mechanism of action, adverse effects and uses of zidovudine. 04
Q.3 Classify antimalarials. Discuss the pharmacology of chloroquine. 06
Write a note on acute toxicity study. 04
Write a note on topical antifungal agents. 04
Q.4 Define and classify immuno-suppressants. Explain their uses. 06
Describe the uses of fibrinolytics and antithrombotics. 04
Explain the mechanism of action and adverse effects of cephalosporins. 04
Q.5 Describe the mechanism of action, adverse effects and uses of tetracyclins. 06
Explain the pharmacology of isoniazid. 04
Discuss the drug interactions and uses of metronidazole. 04
Q.6 Explain the structure of eukaryotic chromosome in detail. 06
Write a note on cell cycle regulators. 04
Describe MAP-kinase pathway. 04
Q.7 Explain the principle and applications of recombinant DNA technology. 06
Describe the factors that affect gene function. 04
Write a note on nucleosomes. 04