Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code:2260005 Date: 01/12/2018
Subject Name: Pharmacology and Pharmacotherapeutics-II
Time:02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Classify DMARDS. Discuss management of rheumatoid arthritis.
06

Discuss pathophysiology, signs and symptoms of epilepsy.
05

Write short note on immunostimulants.
05
Q.2

Discuss the role of neurotransmitters in reward pathways. Write treatment of drug addiction of tobacco.
06

Classify opioid antagonists. Write the clinical indications of the same.
05

Write short note on respiratory stimulants and proconvulsants.
05
Q.3

Write pathophysiology of depression. Discuss in detail SSRIs.
06

Write a note on Benzodiazepines.
05

Discuss the role of excitatory neurotransmitters in neurodegenerative diseases.
05
Q.4

Write pharmacological actions of NSAIDs.
06

Write short note on Aldehyde dehydrogenase inhibitors.
05

Write the physiological and pathophysiological functions of serotonin in CNS.
05
Q.5

Write mechanism of action of general anesthetics. Discuss in detail dissociative anesthetic agent.
06

Discuss in detail pharmacology of Lithium.
05

Justify the use of Carbidopa and Tolcapone in Parkinsonism.
05
Q. 6

Write mechanism of actions of newer antiepileptic agents.
06

Write a note on pre-anesthetic agents
05

Classify immunosuppressive agents. Write the adverse effects and uses of Methotrexate.
05
Q.7

Discuss pathophysiology of insomnia.
06

Mention the class and therapeutics use of: Celecoxib, Bupropion, Buprenorphine, Flumazenil, Dextromethorphan.
05

Write short note on inhalational general anesthetic agents.
05