Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: 270006 Date: 28/11/2018
Subject Name: Pharmacology-III
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Classify antibiotics according to its mechanism of action. Discuss the mechanism of bacterial resistance against antibiotics.
06

Explain the mechanism, adverse effects and uses of Cephalosporins.
05

Explain molecular mechanism of action of cell wall synthesis inhibition in detail.
05
Q.2

Define chemotherapy and explain different mechanisms of chemotherapeutic agents.
06

Explain WHO categorization of T.B. patients and recommended dose regimen.
05

Classify antiulcer agents? Write a note on proton pump Inhibitors.
05
Q.3

Classify immunosuppresants. Write mechanism of action and adverse effects of
cyclosporine.
06

Write a note on oxytocics.
05

Write a note on replacement therapy using corticosteroids.
05
Q.4

Classify antimalarial drugs. Describe the mechanism of action and adverse effects of Chloroquine.
06

Give short note on expectorants and classify drugs used in asthma
05

Describe synthesis of nitric oxide. Write therapeutic uses of NO donors.
05
Q.5

Write a short note on life cycle of malarial parasites.
06

Write a short note on expectorants.
05

Give detailed account on estrogens and antiestrogens.
05
Q. 6

Classify oral hypoglycemic agents and differentiate between Sulphonylurea, DPP4 inhibitors and Biguanides.
06

Write the mechanism of action of antileprotic drugs?
05

Write a short note on anthelmintic drugs.
05
Q.7

What is HAART? Discuss pharmacology of reverse transcriptase inhibitors.
06

Classify antiviral drugs on the basis of mechanism of action.
05

Define terms: super infection, malignant tumor, gray baby syndrome, synergism and ototoxicity.
05