Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: 250006 Date: 03/12/2018
Subject Name: Pharmacognosy IV
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks
Q.1

Give a short note on Tracer-technique and its importance in pharmacognosy.
06

Explain Shikimic acid pathway for the biogenesis of alkaloids and amino acids.
05

Give outline of the biosynthetic pathways of Atropine and Anthracene derivatives.
05
Q.2

What is alkaloid? Give chemical classification of alkaloids according to the heterocyclic ring present in their structures, along with examples.
06

Describe pharmacognostic and phytochemical profile of Nux vomica seed.
05

Discuss isolation method and general qualitative phytochemical tests of Alkaloids.
05
Q.3

Explain the saprophytic reproduction of Ergot along with its life cycle.
06

Give biological sources, family, chemical constituents and uses of any two drugs containing volatile liquid alkaloid.
05

Write a detailed pharmacognostic and phytochemical profile of any one anti-cancer alkaloidal drug.
05
.
Q.4

Discuss pharmacognosy, phytochemistry and pharmacology of the bark containing anti-dysentic alkaloidal principles.
06

Write the biological source, family, morphology, chemical constituents and uses of anti-malarial alkaloidal drug.
05

Give pharmacognostic note on Datura leaf.
05
Q.5

Differentiate the following:
Ephedra sinica and Ephedra equisetina
Egyptian Henbane and Indian Henbane
Indian Rauwolfia and African Rauwolfia
06


Give pharmacognostic details of colchicum.
Write the biological source, chemical constituents and uses of Veratrum and Lobelia.
05
05
Q. 6

Give phytochemical tests, used for identification of the following: (Any three)
Tropane alkaloids Indole alkaloids Cinchona alkaloids
Purine alkaloids
06

Write a pharmacognostic note on anti-hypertensive alkaloidal drug.
05

Draw well labeled diagram of transverse section of Quinazoline alkaloid containing drug.
05
Q.7

Give biological source, chemical constituents, pharmacological actions of the alkaloidal drug used in treatment of glaucoma.
06

Elaborate the aspects of stereochemistry with suitable examples of natural products.
05

Write an assay on stereoisomerism of Alkaloids.
05