Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Pharm. SEMESTER I EXAMINATION SUMMER 2018
Subject Code: 910206 Date: 07/05/2018
Subject Name: Clinical and Hospital Pharmacy
Time: 02:30PM TO 05:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Outline the different types of Pharmacoepidemiological studies. Explain the following: 1. Observational and interventional studies 2. Prospective and retrospective studies
06

What is Incidence and Prevalence. Explain incidence and prevalence rate with suitable examples.
05

Classify pharmacokinetic drug interactions with suitable examples (one for each category).
05
Q.2

Give the symptoms and explain management of Organophosphorous poisoning.
06

Enlist various antidotes and their uses in poisoning.
05

Discuss the symptoms and management of alcohol poisoning.
05
Q.3

Explain the use of TDM in individualization of drug dose regimen.
06

Describe in brief the parameters for measurement of Hepatic function.
05

Explain the following: 1. Defined and prescribed daily doses
2. Attributable and relative risk
05
Q.4

Explain the following terms and discuss its management:
1. Iron overload 2. Radiation sickness
06

Discuss the TDM of Phenytoin and Digitalis.
05

Discuss the dose adjustment for patients with renal hepatic disease?
05
Q.5

Explain in General the principles used in management of Poisoning.
06

Discuss the methods used for decontamination of gut and enhancement of elimination of poison.
05

Enumerate the sources of food poisoning. Discuss management of food poisoning in brief.
05
Q. 6

Discuss the composition and importance of Pharmacy and Therapeutic Committee.
06

Define Inventory control and list out the methods for Inventory control in a Hospital setting. Discuss anyone in detail.
05

Write a short note on Hospital Formulary.
05
Q.7

Discuss reasons for medication non-adherence. How will you assess medication adherence.
06

Discuss the role and responsibilities of hospital pharmacist.
05

Discuss the rules pertaining to handling of narcotics in a hospital pharmacy setting.
05