Exam Details

Subject physiology
Paper
Exam / Course
Department
Organization gujarat public service commission
Position lecturer
Exam Date 21, January, 2008
City, State gujarat,


Question Paper

1 Deficiency of iron results in

(A) Aplastic anemia Megaloblastic anemia

(C) Microcytic anemia Normocytic anemia

2 From the following blood cells which one is the smallest in size Red blood cell Neutrophil Monocyte

(D) Small lympbocyte

3 Leucocytosis occurs due to Repeated exposure to radiations Aplasia of bone marrow Acute bacterial infections Cytotoxic drug administration

4 Clotting factor II is Fibrinogen IV is Calcium VII is Fibrin stabilising factor X is Antihemophilic globulin

5 If blood groups of mother as well as child are Father can NOT have grouP group group group

6 In mismatched blood transfusion Recipients cells are agglutinated and haemolysed Donor's cells are agglutinated and haemolysed There is obstructive jaundice All of the above

7 Reticulocytes are normally Present in bone marrow but absent in peripheral blood Absent in bone marrow but present in peripheral blood Present in reticulo endothelial cells but absent in peripheral blood Present in bone marrow as well as in peripheral blood

8 Absolute Eosinophil count is Number of eosinophils per 100 W.B.C. Number of eosinophils per ml of blood Number of eosinophils per cubic mm of blood 4 to 6

9 Bleeding time is prolonged in Hypercalcemia Hemophilia Thrombocytosis Purpura

10 A reliable screening test for platelet function is Prothrombin time Clotting time Clot retraction time None of the above

11 Normal haematocrit value is 45% 55% 50% 60%

12 Saliva contains Pepsin Ptyalin Trypsin Gastrin

13 Oedema can occur due to Increase in blood capillary hydrostatic pressure Decrease in plasma proteins Increased blood capillary permeability All of the above

14 Achalasia is a disorder related to Speech Cerebellum Hydrochloric acid secretion in stomach Cardiac sphincter of oesophagus

15 An important sign of cerebellar lesion is Ataxia Aphasia Dysphagia Achlorhydria

16 Composition of glomerular filterate is same as Plasma Plasma except plasma proteins Intra cellular fluid None of the above

17 Cholecystokinin causes Contraction of gall bladder Increased secretion of bile by hepatocytes Increased secretion of pancreatic juice rich in bicarbonate All of the above

18 Pancreatic juice contains Ptyalin Pepsin Lipase Enterokinase

19 Cephalic phase of gastric secretion is due to Presence of food in mouth Inhibition of vagus nerve Gastric distension Entero gastric reflex

20 Which of the following clearance tests measures renal plasma flow Inulin clearance test Para amino hippuric acid clearance test Urea clearance test Creatiuine clearance test

21 Normal rate of glomerular filteration is

(A) 125 ml/min 125 ml/hr 1.5 l/hr 1.5 l/day

22 Bile salts Are synthesised by hepatocytes Lower surface tension Are normally absent in unne All of the above

23 Pyloric glands of stomach secrete Acid Acid and Pepsin Thin alkaline watery mucin Thick alkaline viscid mucus

24 Segmentation movement of small intestine Is a wave of contraction followed by a wave of relaxation Is a wave of relaxation followed by a wave of contraction Mainly causes mixing of food Mainly causes propulsion of food

25 Following hormone is released when duodenal contents become acidic Secretin Gastrin Cholecystokinin Somatostatin

26 Intra pleural pressure during inspiration becomes More positive More negative Equal to atmospheric pressure Equal to pressure in alveoli

27 Volume of air in lungs at the end of normal expiration is termed as Vital capacity Functional residual capacity Residual volume Expiratory reserve volume

28 Spirometer is useful in measuring all the following EXCEPT Tidal volume Vital capacity Expiratory reserve volume Total lung capacity

29 Haemoglobin combined with carbon dioxide is termed as Carboxy haemoglobin Carbamino haemoglobin Rednced haemoglobin Methaemoglobin

30 Stagnant type of hypoxia is seen In congestive cardiac failure In congenital heart disease In chronic lung disease At high altitude

31 Central chemoreceptors are mainly stimulated by Decreased blood pO2 Increased blood pCO2 Increased blood H ion concentration All of the above

32 Vagal stimulation causes all EXCEPT Decrease in heart rate Decrease in blood pressure Broncho dilation Increase in gastric acid secretion

33 When tidal volume is 500 ml, dead space is 150 ml and rate of respiration is 12 min; the alveolar ventilation is 1500 ml 2400 ml 4200 ml 5100 ml

34 Counter current exchanger system operates at Glomerular capillaries Vasa recta Loop of Henle Collecting ducts

35 Water reabsorption in proximal convoluted tubules Is under control of anti diuretic hormone Varies so as to regulate water balance Is about 60% of glomerular filterate All of the above

36 Hypothalamohypophyseal portal system Controls hormones of posterior pituitary Controls hormones of anterior pituitary Carries ADH and oxytocin to posterior pituitary None of the above

37 Acromegaly Occurs in adults Causes enlargement of membranous bones Increases blood glucose level All of the above

38 About oxytocin following is true, EXCEPT Is released during labor when there is stretch on cervix Causes milk secretion from lactating mammary gland Causes contraction of myoepithelial cells of lactating mammary gland Is regulated by positive feed back mechanism during labor

39 Thyroid hormone Reduces appetite Increases fat deposition m adipose tissue Decreases rate of glycolysis Promotes growth of brain during early fetal life

40 Goitre means Enlarged thyroid gland Hyperthyroidism Deficiency of thyroid stimulating hormone All of the above

41 Sympathetic stimulation causes Constriction of pupil Contraction of detrusor muscle Constriction of arterioles and veins All of the above

42 Following are the actions of glucocorticoids, EXCEPT Increase gluconeogenesis Promote utilization of fatty acids for energy purpose Increase blood glucose level Prevent ketosis

43 Decreased secretion of aldosterone results in Cushing's syndrome Addison's disease Adrenogenital syndrome Myxedema 3ZXN/AJ 7 IConld_ 44 Polydipsia is Excessive urine formation Excessive eating of food Excessive drinking of water All of the above 45 Somatostatin Is an enzyme secreted by stomach Stimulates secretion of insulin and glucagon Is secreted by delta cells of islets of Langerhans Increases blood glucose level 46 Vitamin D Is converted to 25-hydroxycholecalcifcl'ol in kidneys Is converted to 1,2S·dihydroxycholeca1ci.ferol in liver Acts as a hormone when 1,25-dihydroxycholeca1ciferol is formed All of the above

47 Parathyroid hormone Is a steroid Increases calcium excretion in urine Increases calcium deposition in bones Increases calcium absorption from intestine

48 Deficiency of vitamin d results in Rickets Osteoporosis Tetany Osteoarthritis

49 Osmoreceptors are situated in Anterior pituitary Posteri,or pituitary Anterior hypothalamus Posterior wall of atria

50 Hypercalcemia is caused by Tetosterone Parathyroid hormone Cholecalciferol Calcitonin 3ZXN/AJ 8 IC..'d_.

51 Decreased hypothalamic function causes decreased levels of ali, EX EPT Growth hormone Prolactin ACTH TSH

52 Most potent mineralocorticoid secreted is Cortisol II-deoxycorticosterone Aldosterone Androgens

53 In diabetes mellitus Urine volume is 1 litre in a day Ketone bodies in blood are increased Specific gravity of urine is 1010 None of the above

54 Thyroid gland releases all, EXCEPT Thyrocalcitonin T4. TSH

55 Thirst is initiated by injecting hypertonic saline in which area of hypothalaml.1S Supraoptic nucleus Preoptic nucleus Paraventricular nucleus Posterior hypothalamus

56 Hormone associated with cold adaptation is Melanocyte-stimulating hormone Growth hormone Insulin Thyroxine

57 Life span of sperm ill female genital tract is 1-2 DllD 1-2 hrs 1-2 days 1-2 months

58 All the statements about descent of testes are true, EXCEPT 'failure of descent of testes is called cryptorchidism Normal spermatogenesis fails to occur in undescended testes Temperature of testes is higher in scrotum Hormone testosterone is responsible for the descent 3ZXN/AI 9 [Con"I­

59 Testosterone secretion is controlled by Spermatogenesis Luteinising hormone Follicle stimulating honnone All of the above

60 Hormone which is directly responsible for puberty changes in males is Gonadotropin releasing hormone Gonadotropic hormone Testosterone None of the above

61 Hormone responsible for preovulatory phase of ovarian cycle LH FSH Progesterone None of the above

62 Irrespective of the duration of ovarian cycle, ovulation always occurs 14 days after ODset of menstruation . 14 days before onset of next menstruation ee) Exactly during mid cycle All of the above

63 Fertile period of female sexual cycle is CA) During menstrual phase First 8 days after menstrual phase ee) One day prior to one day after ovulation 4 days before initiation of menstrual phase 64-Rise in body temperature by 0.5 degree F in postovulatory phase is due to Oestrogen Progesterone FSH All of the above

65 Presence of the following in urine is the basis of pregnancy diagnosis test Oestrogen Progesterone Human chorionic somatostatin CD) Human chorionic gonadotropin 3ZXN/A) 10 {Contd_.

66 Following statements are true for corpus luteum, EX EPT Secretes progesterone Increases in size and life span during pregnancy Is responsible for ovulation Is essential for maintenance of pregnancy during first trimester

67 After vasectomy There are no sperms in semen There is no testosterone secretion Male secondary sexual characters disappear All of the above G8 During action potential opening of activation gates of Na channels causes Depolarisation Repolarisation Positive after potential Negative after potential

69 Saltatory conduction Requires more energy Has faster rate of conduction Occurs in unmyelinated nerve fibre All of the above

70 Depolarisation in a nerve fibre is due to Na ion influx K ion influx K ion emux Nat-ion effiux

71 Chronaxie is minimum in (Al Skeletal muscle fihre Cardiac muscle fibre Large myelinated nerve fibre Small unmyelinated nerve fibre

72 Among the muscles Smooth muscle has poorly developed sarcoplasmic-T tubular system Cardiac muscle has one T-tubule per sarcomere Skeletal muscle is most excitable All of the above 3ZXN/AJ II ICooIL

73 "e" group nerve fibres Are of large diameter Have slowest rate of conduction Carry impulses from Ruffini's end organs Supply Meissner's corpuscles

74 "A gamma" type of nerve fibres supply ExtrafusaJ skeletal muscle fibres IntrafusaJ fibres of. muscle spindle AnnuJospiral endings of muscle spindle Smooth muscle fibres

75 Neurotransm..itter at neuromuscular junction is Epinephrine Norepinephrine Serotonin Acetylcholine

76 Unidirectional conduction is seen in Motor nerve fibres Sensory nerve fibres Synapse All of the above

77 Resting membrane potential in SA nodal fibres is -90 mv 49 mv Stable Unstable

78 Inotropic effoct in heart relates to Excitability of cardiae mwcle Heart rate Conduction speed of cardiac impulse Force of contraction of heart

79 During cardiac cycle . AV valves remain closed during isometric contraction phase Sem.iluna! valves open at the beginning of rapid ejection phase Closure of semilunar valves produces second heart sound All of the above

80 Normal ejection fraction is 20% GO% 90% 3ZXN1AI 12 (Coold_

81 Stroke volume is Volume of blood ejected out by left ventricle in I sec Volume of blood ejected out by each ventricle in 1 heart beat Volume of blood ejected out by right ventricle in 1 min Difference in volume of blood ejected out by left and right ventricles

82 Within physiological limits venous return to the heart Decreases heart rate Increases cardiac output Decreases systolic blood pressure None of the above

83 Heart rate Increase is knovm as bradycardia Increases with increase in vagal tone Is low in hyperthyroidism Is low in athletes under resting condition

84 P wave of ECG occurs Before atrial contraction begins (Bj At the end of atrial contraction At the beginning of ventricular contraction At the end of ventricular contraction

85 Mary's law states that Heart rate is directly proportional to blood pressure Blood pressure is directly proportional to heart rate Heart rate is inversely proportional to blood pressure Blood pressure is inversely proportional to heart rate

86 During exercise all changes occur, EXCEPT Increased sympathetic tone to heart Increased vagal tone to heart Increased respiration Vasodilatation in exercising muscles 3ZXN/AJ 13 ICo.ld... 87 Renin is A hormone An enzyme "A powerful vasoconstrictor All of the above 88 First heart sound Is produced due to closure of semilunar valves Is best heard in aortic area Has higher pitch than second heart sound None of the above 89 Coronary blood flow is maximum m Rapid ejection phase Slow ejection phase Isometric contraction phase Isometric relaxation phase 90 Which of the following has fastest rate of impulse conduction Atrial muscle fibres AV Nodal fibres Ventricular muscle fibres Purkinje fibres of ventricular muscle 91 Anterior spinothalamic tract carries sensation of Crude touch Fine touch Pain and temperature Vibration 92 In spinal cord Posterior horn cells are motor Anterior horn cells are sensory Anterior horn cells are of alpha and gamma type All of the above 93 Following is an example of monosynaptic reflex Withdrawal reflex Stretch reflex Golgi tendon reflex Rigbting reflex 3ZXN/A) 14 IContlL. 94 Thalamus is sensory relay station for all, EXCEPT Visual sensation Auditory sensation Olfactory sensation Proprioception 95 Increase in Salivary secretion at the sight of food is Conditioned reflex Unconditioned reflex Is due to vagus nerve None of the above 96 In hemisection of spinal cord, below the level of lesion there is Loss of pain and temperature sensations on the same side Loss of deep sensations on opposite side Upper motor neurone lesion on the same side Lower motor neurone lesion on the opposite side 97 Parkinson's disease is due to damage of Putamen Globus pallidus Dopaminergic cells of substantia mgra All of the above 98 Delta waves in EEG occur during Deep sleep Ligbt sleep REM sleep Awake state 99 FoUowing is a superficial reflex Knee jerk Abdominal reflex Micturition reflex Enterogastric reflex 100 Lower motor neuron lesion is associated with Loss of touch sensation Hypotonia Exaggerated tendon relex ltigidity 3ZXN/AI 15 [Coold-. SPACE FOR ROUGH WORK .. 3ZXN/AI 16 12161


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