Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Pharm SEMESTER-I • EXAMINATION SUMMER-2017
Subject Code: 910101 Date: 29/04/2017
Subject Name: Advanced Organic Chemistry-I
Time: 10:30 AM to 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Write a note on Walden inversion and give the differences between SN1 and SN2 reactions with examples
06

What is Free radical? Write a note on Free radical stability and reactivity
05

Write a note on sulphur and nitrogen Y-lides
05
Q.2

Explain Hoffman and saytzeff's rule for elimination with examples
06

Write a note on Beckman rearrangement
05

Write a note on carbanion and carbene
05
Q.3

Write in detail Claisen condensation with example
06

Write a note on electrophilic addition reaction
05

Write a note on Nucleophilic addition reaction with example
05
Q.4

Explain in detail theory, energy transfer and characteristics of photoreactions
06

Write a note on Hoffmann rearrangement
05

Explain Resonance and Hyperconjugation
05
Q.5

Write a note on AAc2 and BAc2 with suitable example
06

Write a short note on Transannular rearrangement.
05

What is polarity? Explain how it affects the physical properties of a molecule with examples?
05
Q. 6

Write a note on Aromaticity. Explain with example Nucleophilic aromatic substitution reaction.
06

Write a short note on addition and rearrangements of free radicals
05

Explain various factors affecting the reactivity of reaction
05
Q.7

Explain briefly the mechanism and reactivity of E2 reaction with example
06

Write a note on Electrophilic substitution in Aromatic systems.
05

Write a note on Keto-enol tautomerism with example
05