Exam Details
| Subject | bioavailability & therapeutic drug monitoring | |
| Paper | ||
| Exam / Course | b.pharm | |
| Department | ||
| Organization | Gujarat Technological University | |
| Position | ||
| Exam Date | May, 2017 | |
| City, State | gujarat, ahmedabad |
Question Paper
Seat No: Enrollment No:
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM.-SEMESTER-VIII- EXAMINATION -SUMMER-2017
Subject Code: 2280008 Date: 09/05/2017
Subject Name: Bioavailability Therapeutic Drug Monitoring
Time: 10:30 AM to 01:30 PM Total Marks: 80
Instruction:
1. Attempt Any five Questions
2. Make Suitable Assumption wherever necessary
3. Figures to the right indicate full Marks
Q.1
Define TDM. Write down Objective Clinical Application of TDM
Write short note on Physico& Chemical Parameter of Drug body Fluid
Describe the objectives of Bioavailability
Q.2
What are different types OF Study Design? Give detail of Parallel crossover Study Design
Write Target Drug range for TDM
Write down Criteria for Selection of Methods For TDM
Q.3
Enumerate the physical immunoassay in TDM. Write in detail about ELISA
Write a note on Determination of AUC
Define terms: Pharmaceutical Equivalent Bioequivalence
Q.4
Write in Detail about Radioimmunoassay
Explain Relative Absolute Bioavailability
Write down TDM for Phenytoin
Q.5
Enumerate Different Techniques for Enhancement of Bioavaibility. Discuss any one in detail
Write down TDM for Digoxin
Explain Different Methods To assess Bioavailability
Q.6
Explain factors affecting Bioavailability
Write short note on Invitro-Invivo Correlation
Enumerate the different theory of Dissolution. Discuss in detail about Film Theory
Q.7
Explain in detail about Protocol preparation for Pharmacokinetic Equivalence Study.
What is First pass Clearance? How it Will affect Bioavaibility
Discuss about Pharmacodynamic Models
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM.-SEMESTER-VIII- EXAMINATION -SUMMER-2017
Subject Code: 2280008 Date: 09/05/2017
Subject Name: Bioavailability Therapeutic Drug Monitoring
Time: 10:30 AM to 01:30 PM Total Marks: 80
Instruction:
1. Attempt Any five Questions
2. Make Suitable Assumption wherever necessary
3. Figures to the right indicate full Marks
Q.1
Define TDM. Write down Objective Clinical Application of TDM
Write short note on Physico& Chemical Parameter of Drug body Fluid
Describe the objectives of Bioavailability
Q.2
What are different types OF Study Design? Give detail of Parallel crossover Study Design
Write Target Drug range for TDM
Write down Criteria for Selection of Methods For TDM
Q.3
Enumerate the physical immunoassay in TDM. Write in detail about ELISA
Write a note on Determination of AUC
Define terms: Pharmaceutical Equivalent Bioequivalence
Q.4
Write in Detail about Radioimmunoassay
Explain Relative Absolute Bioavailability
Write down TDM for Phenytoin
Q.5
Enumerate Different Techniques for Enhancement of Bioavaibility. Discuss any one in detail
Write down TDM for Digoxin
Explain Different Methods To assess Bioavailability
Q.6
Explain factors affecting Bioavailability
Write short note on Invitro-Invivo Correlation
Enumerate the different theory of Dissolution. Discuss in detail about Film Theory
Q.7
Explain in detail about Protocol preparation for Pharmacokinetic Equivalence Study.
What is First pass Clearance? How it Will affect Bioavaibility
Discuss about Pharmacodynamic Models
Subjects
- agronomy and forestry of medicinal plants
- anatomy physiology & health education -ii
- anatomy, physiology and health education (aphe)
- applied mathematics (biostatistics)
- basic computer applications
- basic concepts of pharmacology and clinical pharmacy practice
- basics of computer applications
- bioavailability & therapeutic drug monitoring
- bioavailability and therapeutic drug monitoring
- biochemistry
- clinical pharmacy ii
- clinical pharmacy-i
- commerce of herbs and phytoconstitutents
- computer applications in drug discovery
- current advances in novel drug delivery systems
- cyber security
- disaster management
- dispensing pharmacy i
- dispensing pharmacy i and drug store management
- dispensing pharmacy ii and pharma industrial management
- dosage form design –i
- dosage form design- i
- dosage form design- ii
- dosage form design-i
- dosage form design-ii
- drug approval process
- environmental studies
- environmental toxicology and green audit
- food analysis
- forensic pharmacy
- forensic pharmacy-i
- genetic engineering and gene therapy
- green chemistry
- health education and community health
- herbal cosmetics
- hospital and community pharmacy
- hospital management and medical tourism
- hospital pharmacy, community pharmacy & forensic pharmacy
- hospital pharmacy, community pharmacy and dispensing pharmacy-ii
- human anatomy physiology
- human anatomy physiology and health education-ii
- human anatomy physiology-ii
- human anatomy, physiology and health education - i
- innovations in conventional drug delivery system
- instrumental and process validation
- intellectual property rights and patents
- medical writing and coding
- medicinal biochemistry
- nutraceuticals
- pathophysiology
- pharmaceutical analysis ii
- pharmaceutical analysis iii
- pharmaceutical analysis iv
- pharmaceutical analysis-i
- pharmaceutical analysis-ii
- pharmaceutical analysis-iv
- pharmaceutical chemistry – ii
- pharmaceutical chemistry – vi (organic chemistry – ii)
- pharmaceutical chemistry –viii (medicinal chemistry - ii)
- pharmaceutical chemistry iii
- pharmaceutical chemistry iv
- pharmaceutical chemistry vii
- pharmaceutical chemistry-i
- pharmaceutical chemistry-i (inorganic chemistry)
- pharmaceutical chemistry-ii (physical chemistry)
- pharmaceutical chemistry-iii (biochemistry – i)
- pharmaceutical chemistry-iv (organic chemistry-i)
- pharmaceutical chemistry-ix (medicinal chemistry-iii)
- pharmaceutical chemistry-v
- pharmaceutical chemistry-v (biochemistry-ii)
- pharmaceutical chemistry-vi (medicinal)
- pharmaceutical chemistry-vii
- pharmaceutical chemistry-viii
- pharmaceutical chemistry-x
- pharmaceutical chemistry-x (medicinal chemistry-iii)
- pharmaceutical engineering
- pharmaceutical engineering-ii
- pharmaceutical inorganic chemistry
- pharmaceutical marketing management
- pharmaceutical microbiology - i
- pharmaceutical microbiology & biotechnology i
- pharmaceutical microbiology &biotechnology- ii
- pharmaceutical microbiology and biotechnology - ii
- pharmaceutical organic chemistry
- pharmaceutical technology - i
- pharmaceutical technology – i
- pharmaceutical technology- ii
- pharmaceutical technology-i
- pharmaceutical technology-ii
- pharmaceutics-i
- pharmaceutics-ii
- pharmaceutivcal chemistry ix
- pharmacognosy iii
- pharmacognosy iv
- pharmacognosy vi
- pharmacognosy vii
- pharmacognosy vii (herbal formulations & complimentary therapies)
- pharmacognosy-i
- pharmacognosy-ii
- pharmacognosy-iii
- pharmacognosy-iv
- pharmacognosy-v
- pharmacognosy-v (plant bio technology)
- pharmacognosy-vi
- pharmacology -iii
- pharmacology & pharmacotherapeutics-ii
- pharmacology and pharmacotherapeutics - i
- pharmacology and pharmacotherapeutics - iii
- pharmacology and pharmacotherapeutics-iv
- pharmacology-i
- pharmacology-ii
- pharmacovigilance
- pharmacy practice
- physical pharmaceutics-ii
- physical pharmacy
- quality by design (qbd) and process analytical technology (pat)
- regulatory aspects of food and neutraceuticals
- remedial mathematics
- unit operation - i
- unit operation - ii