Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm. SEMESTER-II EXAMINATION SUMMER-2017
Subject Code: 2220003 Date: 05/06/2017
Subject Name: Pharmaceutical Analysis II
Time: 10:30 AM to 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Explain the following terminology (Any three)
Chromatography Resolution Capacity factor Dead time
06

Describe classification of chromatography.
05

Explain in detail van Deemeter equation.
05
Q.2

Describe the oxygen combustion flask method.
06

Describe advantages and limitation of instrumental method of analysis.
05

What are electroanalytical methods? Explain classification of electroanalytical methods.
05
Q.3

Explain the following terminology (Any three)
Validation Equivalent conductance Conductivity cell
Gasometric method.
06

Discuss factors affecting conductance.
05

Explain different types of conductometric titration.
05
Q.4

Write the principle, working and limitations of Glass electrode.
06

Discuss method of detecting end point by potentiometry titration.
05

Enlist different reference electrode used in potentiometer and explain any one in detail.
05
Q.5

Explain the following terminology (Any three)
Signal to noise ratio Limiting current Residual current
Specific rotation
06

Discuss Biamperometric titration.
05

Describe normal pulse polarography and differential pulse polarography.
05
Q. 6

Define Extraction. Write a note on continuous extraction.
06

What is calorimetry? Describe principle and instrumentation of TG method.
05

Write a note on DSC.
05
Q.7

Write a note on paper chromatography.
06

Write a note on Dropping mercury electrode.
05

Explain principle and instrumentation of polarimetry.
05