Exam Details
| Subject | pharmacology-i | |
| Paper | ||
| Exam / Course | b.pharm | |
| Department | ||
| Organization | Gujarat Technological University | |
| Position | ||
| Exam Date | May, 2017 | |
| City, State | gujarat, ahmedabad |
Question Paper
1/2
Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEM- IV EXAMINATION SUMMER 2017
Subject code: 240005 Date: 06/05/2017
Subject Name: Pharmacology-I
Time: 02:30 PM to 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Write advantages and disadvantages of oral route of drug administration. What is first pass effect?
06
Describe factors modifying drug action.
05
Write a note on Phases of Clinical Trials.
05
Q.2
What is receptor? Explain Receptor Occupation Theory.
06
What is Glaucoma? Discuss mechanism of actions, pharmacological effects and side effects of pilocarpine.
05
Define
1. Volume of distribution
2. Partial agonist
3. Bioavailability
4. Drug Dependence
5. Potency
05
Q.3
Differentiate between
1. Tachyphylaxis and Tolerance
2. Graded response and Quantal response
06
What is Myasthenia gravis? Discuss indications, pharmacological actions and toxic effects of Neostigmine.
05
Classify adrenoceptor antagonists. Explain pharmacological actions and uses of propranolol.
05
Q.4
Write a note on "Enzyme induction" and "Enzyme inhibition".
06
Classify local anaesthetics. Explain mechanism of action, uses and toxicity of lidocaine.
05
Explain various types of hypersensitivity reactions.
05
Q.5
Classify and discuss Adverse Drug Reactions.
06
Enlist mechanisms involved in drug absorption. Describe Fick's law of passive diffusion in detail.
05
Classify H1 receptor antagonist. Write pharmacological characteristics, therapeutic uses and adverse effects of second generation antihistaminics.
05
2/2
Q. 6
Explain biosynthesis and pharmacological actions of Prostaglandins.
06
Explain phases of Biotransformation with suitable examples.
05
Classify 5-HT receptors. Discuss pharmacological actions of serotonin.
05
Q. 7
Explain biosynthesis and pharmacological actions of angiotensin.
06
Define therapeutic index How to calculate TI? Explain limitations of TI.
05
Write a note on
1. Substance P
2. Neuromuscular blockers
05
Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEM- IV EXAMINATION SUMMER 2017
Subject code: 240005 Date: 06/05/2017
Subject Name: Pharmacology-I
Time: 02:30 PM to 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Write advantages and disadvantages of oral route of drug administration. What is first pass effect?
06
Describe factors modifying drug action.
05
Write a note on Phases of Clinical Trials.
05
Q.2
What is receptor? Explain Receptor Occupation Theory.
06
What is Glaucoma? Discuss mechanism of actions, pharmacological effects and side effects of pilocarpine.
05
Define
1. Volume of distribution
2. Partial agonist
3. Bioavailability
4. Drug Dependence
5. Potency
05
Q.3
Differentiate between
1. Tachyphylaxis and Tolerance
2. Graded response and Quantal response
06
What is Myasthenia gravis? Discuss indications, pharmacological actions and toxic effects of Neostigmine.
05
Classify adrenoceptor antagonists. Explain pharmacological actions and uses of propranolol.
05
Q.4
Write a note on "Enzyme induction" and "Enzyme inhibition".
06
Classify local anaesthetics. Explain mechanism of action, uses and toxicity of lidocaine.
05
Explain various types of hypersensitivity reactions.
05
Q.5
Classify and discuss Adverse Drug Reactions.
06
Enlist mechanisms involved in drug absorption. Describe Fick's law of passive diffusion in detail.
05
Classify H1 receptor antagonist. Write pharmacological characteristics, therapeutic uses and adverse effects of second generation antihistaminics.
05
2/2
Q. 6
Explain biosynthesis and pharmacological actions of Prostaglandins.
06
Explain phases of Biotransformation with suitable examples.
05
Classify 5-HT receptors. Discuss pharmacological actions of serotonin.
05
Q. 7
Explain biosynthesis and pharmacological actions of angiotensin.
06
Define therapeutic index How to calculate TI? Explain limitations of TI.
05
Write a note on
1. Substance P
2. Neuromuscular blockers
05
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