Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM. SEMESTER-I • EXAMINATION -SUMMER 2017
Subject Code: 210003 Date: 01/06/2017
Subject Name: Pharmaceutical Chemistry-I
Time: 02:30 PM to 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Explain the following terms:
1. Hyperkalemia 2. Preservatives 3. Sedative
4. Buffers 5. Astringents 6. Protectives
06

Define limit test. Write a detailed note on limit test for iron.
05

Define impurities. Describe the sources of impurities.
05
Q.2

Give the synonyms and uses of following
1. Common salt 2. Chlorinated lime 3. Baking soda
4. Rochelle salt 5. Slaked lime 6. Green vitriol
06

Write a note on Antioxidants
05

Clarify: Water for injection, sterile water for injection and purified water I.P.
05
Q.3

Distinguish between
1. Poison and Antidote
2. Hypochlorhydria and Hyperchlorhydria
3. Hyponatremia and Hypernatremia
06

Discuss the factors affecting selection of Pharmaceutical buffers and
name any two physiological buffers and two analytical buffers.
05

White down application of Radiopharmaceuticals.
05
Q.4

Comment on the following
Nitrobenzene is used in assay of ammonium chloride.
Magnesium sulphate is used in the assay of calcium lactate.
Polyhydroxy alcohol is used in assay of boric acid.
06

Define Pharmacopeia. Give a brief note on Indian Pharmacopeia
05

Write a note on chelating agents used in therapy.
05
Q.5

Give an account on method of preparation and uses of hydrochloric acid.
06

What are antacids? Outline the ideal requirements of an antacid.
05

Write a short note on dental products.
05
Q. 6

Give method of preparation and category of following compounds.
1. Potassium chloride
2. Silver nitrate
3. Sodium carbonate
06

Write a note on oral rehydration salt.
05

Discuss the biological importance of calcium.
05
Q.7

Define haematinic. Write about various haematinic preparations.
06

Discuss at length on dried aluminium hydroxide gel.
05

How the radioactivity measured? Write a note on GM counter.
05