FACULTY OF PHARMACY
B. Pharmacy 3/4 I-Semester (Suppl.) Examination, April 2018
Subject Physical Pharmacy-I
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Explain the postulates of the kinetic molecular theory.
Explain the methods to achieve liquefaction of gases.
Write about polymorphism and its applications in pharmacy.
OR
State Gibbs phase rule. Explain the phases diagram of phenol-water system.
Write a note on refractive index and molar refraction with applications.
2 State and explain first and second law of thermodynamics with applications.
Define: Specific heat Latent heat Enthalpy Entropy
OR
Define and explain Hess's law of constant summation. Write its applications.
Explain Gibbs free energy and its function and applications.
3 What are colligative properties? Explain freezing point depression as a
colligative property and its applications.
Discuss the modern theory of strong electrolytes.
OR
Write a note on Sorensen's pH scale.
Derive the equation for determination of acidity and basicity constant and
write its use.
Define Molarity, molality and normality.
4 What are the methods for adjustment of tonicity and pH. Explain cryoscopic
method and sodium chloride equivalent method for adjusting isotonicity.
Write Van Slyke's equation for buffer capacity and maximum buffer capacity
and its applications.
OR
Derive Henderson-Hasselbalch buffer equation for a weak acid and its salt.
Explain is isotonic, hypertonic and hypotonic solutions? Explain its importance.
Write a note on physiological buffers.
5 Explain different types of electrodes.
Write the applications of redox potentials in pharmacy.
OR
Draw and explain Daniel cell.
What is catalysis? Write types of catalysts, catalytic reactions, mechanism
and applications of catalytic reactions.