FACULTY OF PHARMACY
B. Pharmacy 2/4 II Semester (Suppl) Examination, April 2018
Subject Pharmaceutical Biochemistry
Time: 3 Hours Max. Marks: 70
Note: Answer All Questions. All Questions carry Equal Marks.
1. Describe the biochemical organization of cell organelle 8
Discuss the Passive transport across the cell membrane 6
OR
Explain the concept of free energy? 6
Write a note on energy rich compounds 8
Calculate the ATP yield when glucose is completely oxidized via Glycolysis and
Krebs cycle? 8
Discuss about the uronic acid pathway 7
OR
Explain the various steps of Glycogenolysis? 7
Discuss the biodegradation of AC-COA via TCA cycle: and calculate the total ATP
production. 7
What are essential fatty acids. Give their significance? 7
Briefly discuss about the biosynthesis of fatty acids 7
OR
Explain the beta oxidation of fatty acids? 7
Discuss the metabolism of cholesterol? 7
Explain the Principles involved in biological oxidation? 6
Write the biosynthesis of purines? 8
OR
Write in detail about the Biosynthesis of RNA? 7
Explain the mechanism involved in the protein synthesis and it regulation? 7
Describe the principles and methods involved in the quantitative analysis of
Blood Creatinine
ii) Cholesterol.
iii) Urinary Ketone bodies
iv) Urinary glucose. 31/2 x 4 14
OR
Describe the principles and methods involved in the quantitative analysis of Blood
glucose and phosphates. 7
Describe principle involved in various methods of blood urea determination 7