FACULTY OF PHARMACY
Pharm D. YDC) III Year (Main) Examination, September October 2017
Subject Pharmaceutical Formulations
Time 3 hours Max. Marks 70
Note: Answer all questions from Part-A. Answer any FIVE questions from Part-B.
PART A (10 x 2 20 Marks)
1. Describe the weight variation test for hard gelatin capsules. 2
2. Give the use of tablet coating and the types of coatings. 2
3. Describe the disintegration test for enteric coated tablets. 2
4. Define flocculation, coalescence and granulation. 2
5. List the quality control tests of emulsions. 2
6. Describe the LAL test for parenterals. 2
7. Define creams, ointments, pastes and gels. 2
8. List out the different types of glasses with their purpose of use in pharmaceutical
packaging. 2
9. Define transdermal and implant systems. 2
10.Define Isotonicity? Give its application in parenterals. 2
PART B x 10 50 Marks)
11. Define the following tabletting problems with the solution to overcome. 10
Picking and sticking ii) Mottling iii) Orange peel effect
iv) Capping and Lamination
12. Discuss the preparation of soft gelatin capsules with a neat diagram. 10
13.a) Describe the preparation of emulsion with the following methods. 7
Bottle method ii) Wet gum method iii) Dry gum method
Explain about the freeze-thaw cycle for evaluation of emulsions. 3
14. Discuss about the different suppository bases with their advantages and limitations. 10
15.a) Describe the general considerations for the preparation of eye ointments. 6
Add a note on preparation of eye ointment. 4
16.a) Write a note on theories of emulsification. 4
Discuss the principle and method of preparation of cold cream. 6
17. List out the different types of oral controlled release systems with their mechanism
of drug release. 10
18.a) Differentiate between large volume and small volume parenterals. 5
Write about the different containers used for parenterals. 5