FACULTY OF PHARMACY
Pharm. D YDC) III-Year (Main) Examination, July 2017
Subject Pharmacology II
Time 3 Hours Max. Marks: 70
Note: Answer all questions from Part A and answer any five questions from Part-B.
PART A (10 x 2 20 Marks)
1 What are anticoagulants? Write their therapeutic uses.
2 Write a note on Fibrionlytics.
3 Explain about osmatic diuretics.
4 Explain about Acetazolamide.
5 Classify antifungal agent with example.
6 Classify anticancer drugs.
7 Explain about suicidal bags of the cell.
8 What are the principles involved in toxicology?
9 Explain onchogenes and tumor suppressor genes.
10 Define mutations, deletions and amplifications.
PART B x 10 50 Marks)
11 What are the basic principles of transcription in pro and eukaryotes and discuss the factors
that regulate transcription?
12 What are the different toxicity studies? Explain how to design a protocol for chronic toxicity
studies.
13 Explain the mechanism of action, pharmacological activity uses and adverse effects of Loop
Diuretics.
14 What are signal transduction pathways explain any four of them?
15 Write the mechanism of action, therapeutic uses and adverse effects of
Penicillins
Tetracyclines
16 Explain in detail about chemotherapy of tuberculosis.
17 What is Recombinant DNA technology? Write their processes and applications.
18 Describe about gene sequencing and mapping.