FACULTY OF PHARMACY
Pharma. D. II Year (Instant) Examination, January 2018
Subject: Pharmacology I
Time: 3 Hours Max.Marks: 70
Note: Answer all questions from Part A. Answer any five questions from Part B.
PART A (10 x 2 20 Marks)
1 Define the terms tachyphylaxis and teratogenicity. 2
2 What is vasomotor reversal of Dale? 2
3 Give a note on insulin analogues. 2
4 What is triple response? 2
5 Write about the role of prostaglandins on kidney. 2
6 Give the differences between local anaesthetics and general anaesthetics. 2
7 What are Non-steroidal anti inflammatory agents? Classify them. 2
8 Write a note on Platelet activating factor. 2
9 Define Epilepsy and write the mechanism of action of phenytoin. 2
10 Explain about cholinesterases. 2
PART B (50 Marks)
11 Write in detail about factors modifying drug action. 7
Write a note on biotransformation reactions. 3
12 What is congestive heart failure? Write in brief about drugs used in the
treatment of congestive heart failure. 7
Classify hypolipidemic agents. Write a note on statins with examples. 3
13 Give the pharmacology of adrenaline. 7
Write a note on mydriatics and miotics. Give examples. 3
14 Write a note on 5-HT antagonists with examples. 5
Give a detailed note on pharmacological actions of histamine. 5
15 What are hypoglycaemics? Classify oral hypoglycaemics and write in detail
about them. 6
Enumerate the actions of insulin. 4
16 Write notes on
Central nervous system stimulants. 5
Pharmacological actions of Levodopa. 5
17 Define and classify bronchodilators. 3
Explain in detail any two classes of bronchodilators. 7
18 Write short notes on:
Drug Interactions 5
Anti thyroid drugs 5