FACULTY OF PHARMACY
Pharm D YDC) II Year (Main Backlog) Examination, August 2016
Subject: Pathophysiology
Time: 3 Hours Max.Marks: 70
Note: Answer all questions from Part A. Answer any Five questions from Part B.
PART A (10x2 20 Marks)
1 Distinguish between Mania and Depression.
2 Enumerate different types of Angina pectoris.
3 Define the terms Metaplasia and Hyperplasia.
4 Write the deficiency symptoms of vitamin C.
5 Write the pathophysiology of leprosy.
6 Explain the mechanism involved in Autoimmunity.
7 Draw a neat labelled diagram of B-Lymphocytes.
8 Write the clinical manifestations of Acute Renal Failure.
9 Write the biological effects of sulphur dioxide.
10 Represent the pathogenesis of peptic ulcer disease in the form of diagram.
PART B (5x10 50 Marks)
11 Write the etiopathogenesis of AIDS. 10
12 Describe the structure of MHC (Major histocompatability complex) with a neat
labelled diagram. 7
Write the mechanism involved in transplant rejection. 3
13 Write the pathogenesis of hypertension. 6
Differentiate between Ischemic and hemorrhagic stroke. 4
14 Explain the cellular events of inflammation. 6
Write a note on complement system activation. 4
15 Write in detail about RAS gene and P53 tumour suppressor genes. 7
Explain the etiology of cancer. 3
16 Explain in detail about Type II and III Hypersensitivity reactions. 10
17 Write the pathogenesis of Type I Diabetes Mellitus. 5
How are AGEs (Advanced Glycation End products) formed? 5
18 Explain different causes of cell injury. 3
Explain in detail the formation of reactive oxygen species. 7