FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutics I-Semester (PCI)(Main Backlog) Examination,
January 2019
Subject Drug Delivery System
Time: 3 Hours Max. Marks: 75
Note: Answer any Five Questions. All Questions Carry Equal Marks.
1. Compare sustained release, delayed release and controlled drug delivery system
with examples? 6
Define pharmacogenetics? Explain telepharmacy? 9
2. What do you mean by activation modulated system? Explain osmotic drug delivery
system? 8
Classify rate controlled drug delivery system? Explain feedback regulated systems 7
3. What are the barriers of buccal mucoadhesive drug delivery system? Mention two
examples of marketed mucoadhesive drug delivery system? 7 7
Explain in detail floating drug delivery systems? 8
4. Describe formulation and evaluation of ocular drug delivery system? 10
What are ocular insitu gels? 5
5. Explain structure of skin? What are barriers of transdermal permeation? What are
the ideal properties of a drug candidate to permeate through the skin? 10
Classify transdermal permeation enhancers? Explain the mechanism of permeation
enhancers? 5
6. Explain in detail various strategies to formulate a stable protein and peptide drug
formulations? 8
Describe physical and chemical stability of protein and peptides? 7
7. Explain in detail mucosal and active transdermal methods of delivering vaccines
through mucosa and skin? 8
Write a note on single shot vaccines? 7
8. Explain various physiochemical and biological factors that influences the SR and CR
formulations? 10
Classify polymers? Explain properties of any two synthetic biodegradable polymers? 5