FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutical Chemistry) I-Semester (Supple.) Examination,
August 2018
Subject: Chemistry of Natural Products
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Discuss the structural elucidation of morphine reserpine.
2 Discuss how natural products acted as leads while designing the drugs?
Explain by taking any three categories of drugs.
3 What are flavanoids? Discuss the structural elucidation of quercetin.
Discuss the chemistry and mechanism of contraceptive steroids.
4 What are isoprene and special isoprene rules? Discuss the structural elucidation
of any one monoterpeniod and one diderpenoid.
5 Write the approximate spectral values for the following natural drugs in IR,
1HNMR and 13CNMR spectra.
Morphine
Any one Digitalis glycoside
Benzyl penicillin
Quercetin
Vitamin D
6 Write a note on
Recombinant DNA technology and drug discovery
Chemistry of Vitamin A
Stereochemistry and nomenclature of steroids
7 Explain how natural products acted as leads in the discovery of new
antibiotics and macrolide antibiotics.
Discuss the structural elucidation of Ephedrine.
8 List out the active constituents that are isolated from the following crude
drugs with their medicinal use
Pterocarpus marsupiam
Swertia chirata
Phyllanthus niruri
Curcuma longa Linn
(b)Write a note on Gene therapy.