FACULTY OF PHARMACY
M. Pharmacy (Pharmacognosy) I-Semester (Main) Examination, February 2018
Subject: Phytochemistry
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Write the chemistry, biosynthesis, mechanism of action and chemical tests for
Digitoxin.
Write the chemistry and analogs of artemesin. 10+5
2 Write about the chemistry of
Quinine
Withanolides
Sennosides
3 Define and write the selection and optimization of lead compounds in Drug
Discovery with suitable examples. 10+5
4 Discuss spectral characters to elucidate the chemical structure of Menthol. 15
5 Write the source, chemical structure and method of isolation of
Quinine ii) Sennosides iii) Piperine.
6 Write a note
Phases of clinical trials
Applications of HPTLC
7 Define and describe different types of extraction and extract techniques with advantages
and disadvantages of each technique. 15
8 Explain the principle, instrumentation, detectors and applications of HPTLC. 15