Exam Details
| Subject | advanced spectral analysis | |
| Paper | ||
| Exam / Course | m. pharmacy (pharm. chemistry) | |
| Department | ||
| Organization | G. Pulla Reddy College Of Pharmacy | |
| Position | ||
| Exam Date | February, 2019 | |
| City, State | telangana, hyderabad |
Question Paper
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutical Chemistry) II-Semester (Suppl.) Examination,
February 2019
Subject Advanced Spectral Analysis
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Write down the wood ward Fieser rules for 1,3-butadienes and -Carbonyl
Compounds. Calculate the max for the following.
How do you know the presence of C NH2, OH, SO2 and NO2 groups in IR?
(Indicate the wave number ranges).
2 Discuss about any two 2-D NMR techniques in interpretation of structure of organic
compounds.
3. Discuss the fragmentation patterns of following functional groups in mass
Spectrometry
Alkanes Carbonyl compounds Amines Alcohols.
Explain Mc Lafferty rearrangement.
How do you defect the isotopic peaks in mass spectrometry?
4. Discuss the principle, instrumentation and applications of any two of the following:
GC-MS HPTLC Flash chromatography
5. Discuss the principle, instrumentation and applications of
DSC Raman Spectroscopy
6. Explain the principle and applications of ELISA
Discuss radio immune assay of insulin
7. Write a note on the following (any two)
Super Critical fluid chromatography
LC-MS
Ion-exclusion chromatography
8. Draw a rough 'HNMR Spectra for the following with proton splitting pattern
Where shall we expect the C=O strechings for the following aromatic compounds?
Aldehydes Ketones Carboxylic acids esters
-lactams amides anhydrides
Unsaturated carbonyl compounds
M. Pharmacy (Pharmaceutical Chemistry) II-Semester (Suppl.) Examination,
February 2019
Subject Advanced Spectral Analysis
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Write down the wood ward Fieser rules for 1,3-butadienes and -Carbonyl
Compounds. Calculate the max for the following.
How do you know the presence of C NH2, OH, SO2 and NO2 groups in IR?
(Indicate the wave number ranges).
2 Discuss about any two 2-D NMR techniques in interpretation of structure of organic
compounds.
3. Discuss the fragmentation patterns of following functional groups in mass
Spectrometry
Alkanes Carbonyl compounds Amines Alcohols.
Explain Mc Lafferty rearrangement.
How do you defect the isotopic peaks in mass spectrometry?
4. Discuss the principle, instrumentation and applications of any two of the following:
GC-MS HPTLC Flash chromatography
5. Discuss the principle, instrumentation and applications of
DSC Raman Spectroscopy
6. Explain the principle and applications of ELISA
Discuss radio immune assay of insulin
7. Write a note on the following (any two)
Super Critical fluid chromatography
LC-MS
Ion-exclusion chromatography
8. Draw a rough 'HNMR Spectra for the following with proton splitting pattern
Where shall we expect the C=O strechings for the following aromatic compounds?
Aldehydes Ketones Carboxylic acids esters
-lactams amides anhydrides
Unsaturated carbonyl compounds
Other Question Papers
Subjects
- advanced medicinal chemistry
- advanced organic chemistry – i
- advanced organic chemistry-ii
- advanced spectral analysis
- chemistry of natural products
- computer aided drug design
- modern pharmaceutical analytical techniques
- pharmaceutical process chemistry