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P.T.O.
MAR IVANIOS COLLEGE (AUTONOMOUS)
THIRUVANANTHAPURAM
Reg. No. :.………………… Name :.…………………
Fourth Semester Career Related B.Sc. Degree Examination, June 2016
First Degree Programme under CBCSS Vocational Course (for Botany and Biotechnology)
AUBB451: Molecular Biology
Time: 3 Hours Max. Marks: 80
SECTION A
Answer ALL the following in a word or one or two sentences.
1. Codons
2. Intron
3. DNA polymerase
4. Peptidyl transferase
5. Polysomes
6. Promoter
7. Aminoacyl tRNA synthetases.
8. Sigma factor
9. Chargaff's rule
10. Sense strand
(10 × 1 10 Marks)
SECTION B
Answer any EIGHT questions, not exceeding a paragraph.
11. Write notes on RNA localization and RNA decay.
12. What is ubiquitin
13. Semiconservative model of DNA replication.
14. Name structural genes in lac operon.
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15. Describe the Structure of tRNA.
16. Identify two promoter regions of a prokaryote.
17. What is wobble hypothesis
18. List the start and stop codons.
19. What are regulatory sequences in eukaryotes
20. Name any four enzymes involved in DNA replication.
21. What is Klenow fragment
22. What are snRNPs
× 2 16 Marks)
SECTION C
Short essay type Answer any SIX questions.
23. How is replication different in leading and lagging strand
24. Explain RNA localization and RNA decay.
25. Elongation process in translation.
26. Write short note on nucleosome.
27. Brief about the various post transcriptional modifications undergone by mRNA.
28. Explain the genetic code with its properties.
29. Differentiate prokaryotic and eukaryotic transcription.
30. Explain Heterochromatin and euchromatin.
31. Write short notes on mitochondrial DNA with its Genes.
× 4 24 Marks)
SECTION D
Long essay type Answer any TWO questions.
32. Detail the regulated functioning of lac operon, with suitable diagrams.
33. Describe the transcription process in prokaryotes.
34. Explain different types of transposable elements and its significance.
35. Explain post translational modifications of proteins.
× 15 30 Marks)