(Pages 1596
P.T.O.
MAR IVANIOS COLLEGE (AUTONOMOUS)
THIRUVANANTHAPURAM
Reg. No. :.………………… Name :.………………….
Third Semester B.Sc. Degree Examination, November 2016
First Degree Programme under CBCSS
Foundation Course II
AUZO321: Methodology and Perspectives of Science and Bioinformatics
Time: 3 Hours Max. Marks: 80
SECTION A
Answer ALL questions in one or two sentences.
1. Define empiricism
2. What is the resolving power of a microscope
3. What is Rf value
4. Define mode
5. Comment on test of significance.
6. What is patent
7. Expand BRNET
8. Expand NCBI
9. Define proteomics
10. What is molecular phylogenetics
(10 1 10 Marks)
SECTION B
Answer any TEN questions, each in a short paragraph not exceeding 50 words.
11. Differentiate between scientific theory and scientific law with a suitable example.
12. What is scientific temper
13. Differentiate between inductive reasoning and deductive reasoning.
14. Comment on the working principle of bright field microscope.
15. Explain density gradient centrifugation.
16. What is micrometry
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17. List the merits and demerits of as a „measure of central tendency‟.
18. What is statistical data What are the important aspects associated with statistical data
19. Comment on null hypothesis.
20. What is plagiarism
21. What is INFLIBNET
22. Differentiate between PAM and BLOSUM.
23. Comment on the uses of multiple sequence alignment.
24. What is PHYLIP
25. Define personalized medicine. Give any two advantages of Personalized medicine.
(10 2 20 Marks)
SECTION C
Answer any SIX questions, each in a paragraph not exceeding 120 words.
26. Comment on the principles which form the basis for scientific laws.
27. Differentiate between colorimetry and spectrophometry.
28. Give an account of phase contrast microscope.
29. Comment on the characteristics and uses of Chi square test.
30. The percentage of water, lipid, protein and other materials are and 21% respectively in the body of a species of fish. Construct a pie chart to represent this data.
31. Briefly discuss the different forms of scientific misconduct.
32. "Internet is truly a knowledge repository". Justify this statement.
33. What is FASTA List the programmes under FASTA
34. Give an account of drug discovery pipeline.
5 30 Marks)
SECTION D
Answer any TWO questions, not exceeding four pages.
35. Give an account of chromatography and its applications.
36. Describe the various methods employed for presenting scientific data.
37. Write an essay on the popular databases in bioinformatics.
38. Briefly describe the various bioinformatics tools.
10 20 Marks)