BP 103 T
Professional Course Examination, November 2018
CBCS
1st Semester
BACHELOR OF PHARMACY
Pharmaceutics—I
Full Marks 75
Time 3 hours
The figures in the margin indicate full marks for the questions
I. Choose the correct answer from the following 1×20=20
1. Second edition of the Indian Pharmacopoeia was published in the year
1996
1946
1955
1966
2. The sign Rx in a prescription is known as
superscription
inscription
subscription
signa
/477 1 Contd.
3. British Pharmacopoeia was prepared by merging three existing
Pharmacopoeias of the time. Which is not one of them?
London Pharmacopoeia
Dublin Pharmacopoeia
Scotland Pharmacopoeia
Edinburgh Pharmacopoeia
4. Age in years
20
is one of the child dose calculation methods, it is called
Dilling's rule
Young's rule
Catzel's rule
Surface area method
5. Which of the following is not intended for application to the skin?
Liniments
Lotions
Lozenges
Collodions
/477 2 Contd.
6. Viscous, liquid oral preparations that are usually prescribed for the
relief of cough are called
paints
pessaries
poultices
linctuses
7. The most extensively used solid dosage form is
capsules
powders
tablets
suspensions
8. One fluid ounce is approximately equivalent to
100 ml
15 ml
50 ml
30 ml
9. To prepare 600 ml of 60% alcohol from 95% alcohol, the volume of the
95% alcohol required is
379 ml
250 ml
360 ml
100 ml
/477 3 Contd.
10. Consider the following statements
I. Purified talc has excellent flow and is used in dusting powders.
II. Medical dusting powders are not to be applied on open wounds.
III. Surgical dusting powders are used in body cavities and wounds.
Which of the following options is correct?
I and II are correct, III is false
All are false
Only III is correct
All are true
11. Consider the following statements
I. In effervescent granules, sodium bicarbonate reacts with acids to
product effervescence.
II. In effervescent granules, the quantity of citric and tartaric acids is
slightly more than necessary to neutralize.
III. This is because effervescent preparations are more palatable if
slightly acidic.
Which of the following options is correct?
I and II are correct, III is false
All are false
Only III is correct
All are true
12. Which of the following is not a solubility enhancement technique?
Hydrotropy
Chromatography
Cosolvency
Solid dispersion technique
/477 4 Contd.
13. A clear, liquid oral preparation of potent or nauseous drug is called
elixir
draught
gargles
poultice
14. A mixture of olive oil and water represents
physical incompatibility
chemical incompatibility
therapeutic incompatibility
complex incompatibility
15. Tween 80 has an HLB value of about 15, it will be used to prepare
W/O emulsions
O/W emulsions
W/W emulsions
Any type of emulsions
16. Which of the following is not a test for identifying emulsion type?
Miscibility test
Staining test
Electrical conductivity test
Coring test
/477 5 Contd.
17. Which of the following can cause cracking of an emulsion?
Rapid stirring
Addition of common solvent
Reduction of globule size
Addition of colouring agent
18. Which of the following preparations requires 'Shake well before use'
labelling instruction?
Solutions
Suspensions
Gargles
Ointments
19. Which of the following is not a polysaccharide suspending agent?
Tragacanth
Sodium alginate
Acacia
Bentonite
20. Which of the following contains high proportion of powdered solids in
it?
Ointments
Gels
Pastes
Creams
/477 6 Contd.
II. Answer the following long answer-type questions (any two) 10×2=20
1. What is posology? Discuss different methods of pediatric dose
calculations based on age, body weight and body surface area. 1+9=10
2. Define ointments, pastes, creams and gels. What are different factors
that influence dermal penetration of drugs? Discuss. 4+6=10
3. Compare and contrast between suspensions and emulsions.
Describe the physical, chemical and therapeutic incompatibilities
with suitable examples. 4+6=10
III. Answer the following short answer-type questions (any seven) 5×7=35
1. Briefly discuss the development of USP.
2. Explain the different parts of a prescription.
3. Discuss the flocculated and deflocculated suspension.
4. Discuss briefly the stability problems of emulsions and the methods to
overcome it.
5. Classify different types of suppository bases giving suitable example of
each class.
6. What are syrups? Differentiate between lotions and liniments.
7. What are eutectic mixtures? Explain effervescent, efflorescent and
hygroscopic powders.
8. Discuss different solubility enhancement techniques.
9. Discuss different tests for identification of types of emulsions.