Exam Details
| Subject | biopharmaceutics and pharmacokinetics | |
| Paper | ||
| Exam / Course | bachelor of pharmacy | |
| Department | ||
| Organization | Mizoram University | |
| Position | ||
| Exam Date | November, 2018 | |
| City, State | mizoram, |
Question Paper
BPH/VII/58
Professional Course Examination, November 2018
Pre-CBCS
7th Semester
BACHELOR OF PHARMACY
Paper No. 58
Biopharmaceutics and Pharmacokinetics
Full Marks 40
Time 2 hours
The figures in the margin indicate full marks for the questions
Answer any eight questions
1. Discuss the role of biopharmaceutics and pharmacokinetic studies in drug
formulation development. 5
2. What is passive diffusion? Discuss the mechanism of drug absorption by
passive diffusion.
3. Explain the influence of particle size of a drug and the dosage form on the
rate and extent of its absorption.
4. Do you agree that 'plasma-bound drugs are pharmacologically inactive'? If
Yes/No, provide your reasons and also briefly explain the significance of
plasma protein binding of drugs.
5. With a neat diagram, differentiate between mammillary and catenary
compartment models. Give an example of an organ that could represent a
central compartment in compartment models.
/497 1 Contd.
6. Write a note on any one of the following 5
Volume of distribution
Mechanism of renal clearance
7. What are the different reasons for non-linearity in pharmacokinetics? How
do you detect such non-linearity?
8. Differentiate between bioavailability and bioequivalence. Define Cmax, tmax
and AUC.
9. Describe the design of a single-dose bioequivalence study. 5
10. Write a note on any one of the following 5
Pharmacokinetic drug interactions
Dosage adjustment in renal patients
Professional Course Examination, November 2018
Pre-CBCS
7th Semester
BACHELOR OF PHARMACY
Paper No. 58
Biopharmaceutics and Pharmacokinetics
Full Marks 40
Time 2 hours
The figures in the margin indicate full marks for the questions
Answer any eight questions
1. Discuss the role of biopharmaceutics and pharmacokinetic studies in drug
formulation development. 5
2. What is passive diffusion? Discuss the mechanism of drug absorption by
passive diffusion.
3. Explain the influence of particle size of a drug and the dosage form on the
rate and extent of its absorption.
4. Do you agree that 'plasma-bound drugs are pharmacologically inactive'? If
Yes/No, provide your reasons and also briefly explain the significance of
plasma protein binding of drugs.
5. With a neat diagram, differentiate between mammillary and catenary
compartment models. Give an example of an organ that could represent a
central compartment in compartment models.
/497 1 Contd.
6. Write a note on any one of the following 5
Volume of distribution
Mechanism of renal clearance
7. What are the different reasons for non-linearity in pharmacokinetics? How
do you detect such non-linearity?
8. Differentiate between bioavailability and bioequivalence. Define Cmax, tmax
and AUC.
9. Describe the design of a single-dose bioequivalence study. 5
10. Write a note on any one of the following 5
Pharmacokinetic drug interactions
Dosage adjustment in renal patients
Other Question Papers
Subjects
- anatomy, physiology and health education—i
- basic electronics and computer applications
- biopharmaceutics and pharmacokinetics
- communication skills
- general and dispensing pharmacy
- human anatomy and physiology—i
- medicinal chemistry—i
- pathophysiology of common diseases
- pharmaceutical analysis—i
- pharmaceutical analysis—iii
- pharmaceutical biochemistry
- pharmaceutical business management
- pharmaceutical inorganic chemistry
- pharmaceutical technology—i
- pharmaceutical unit operation—ii
- pharmaceutics—i
- pharmacognosy—ii
- pharmacognosy—iv
- pharmacognosy—vi
- pharmacology—ii
- pharmacology—iv
- physical pharmacy—i
- remedial biology
- remedial mathematics