BIOTECH/V/CC/13 Student's Copy
2 0 1 8
CBCS
5th Semester
BIOTECHNOLOGY
SEVENTH PAPER
Biostatistics and Bioinformatics
Full Marks 75
Time 3 hours
PART A—OBJECTIVE
Marks 25
The figures in the margin indicate full marks for the questions
SECTION—A
Marks 10
Tick the correct answer in the brackets provided 1×10=10
1. Which of the following retains the information it's storing when the power
to the system is turned off?
CPU
ROM
RAM
DIMM
2. Which of the following is correct?
1 KB 1024 bytes
1 MB 2048 bytes
1 MB 1000 kilobytes
1 KB 1000 bytes
/156 1 Contd.
3. The value of a variable for which the frequency is maximum is known as
median
mode
combined mean
geometric mean
4. When there is a comparison between two or more variables, which type of
bar diagram is used?
Simple bar diagram
Percentage bar diagram
Divided bar diagram
Multiple bar diagram
5. A woman can give birth to either son or daughter. This is an example of
mutually exclusive event
sure event
null event
mixed event
6. A hypothesis for the possible rejection under the assumption that it is true
is known as
alternative hypothesis
null hypothesis
simple hypothesis
complex hypothesis
7. The information retrieval tool of NCBI GenBank is
Entrez
STAG
SeqIn
Text search
BIOTECH/V/CC/13/156 2 Contd.
8. Margaret Dayhoff developed the first protein sequence database called
SWISS PROT
PDB
atlas of protein sequence and structure
protein sequence database
9. The best classification system is one that
unites organisms that possess similar morphology
conforms to traditional and Linnaean taxonomic practices
reflects evolutionary tree
reflects the basic separation of prokaryotes from eukaryotes
10. The alignment method suitable for finding out conserved patterns in DNA
or protein sequence is
multiple sequence alignment
pairwise alignment
global alignment
local alignment
SECTION—B
Marks 15
Write on/Answer the following 3×5=15
1. Memory devices
OR
Concept of files and folders
BIOTECH/V/CC/13/156 3 Contd.
2. Primary and secondary data
OR
In a study of blood groups in 1629 males and 1181 females of Mizoram, the
following data were obtained
Blood
groups
No. of Persons
Male Female Total
A 427 317 744
B 559 412 971
O 521 367 888
AB 122 85 207
Represent the data using suitable diagram.
3. Applications of chi-square test
OR
Correlation analysis
4. Applications of bioinformatics
OR
Specialized genome databases
5. Open reading frame
OR
Fundamentals of phylogenetic analysis
PART B—DESCRIPTIVE
Marks 50
The figures in the margin indicate full marks for the questions
1. What are different types of search engine? Elaborate on any two of them. 10
OR
Explain the input and output devices. 5+5=10
2. Write notes on any two of the following 5+5=10
BIOTECH/V/CC/13/156 4 Contd.
Data classification
Data representation
Measures of central tendency
3. Explain how sampling of data is done citing an example. 10
OR
Describe correlation of data and cite an example. 10
4. Describe the primary and secondary databases. 10
OR
Describe the protein data bank in detail. 10
5. Define phylogenetic analysis and describe the steps involved in
phylogenetic analysis. 10
OR
Describe the types of sequence alignment with examples. 10