FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
BIOCHEMISTRY
PAPER II
Time 3 hours BIO/D/17/03/II
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two
answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Significance of HMP shunt pathway. Add a note on
G6PD deficiency.
7+3
2. Oxidative phosphorylation
Substrate level phosphorylation
6+4
3. Peptide hormones regulating food intake.
10
4. Chronic complications of diabetes mellitus. Add a note
on Polyol pathway.
6+4
5. Reactive oxygen species and their scavengers.
6+4
6. Protein energy malnutrition, types, clinical and
biochemical features
10
7. Glycemic index
Dietary fibre
5+5
8. Role of selenium as antioxidant
Iron toxicity
5+5
9. Nitric oxide: synthesis and its functions.
Serotonin: synthesis and its role in body.
5+5
10. Methyl trap hypothesis
Biologically 'active' forms of B12
5+5