N A L A N D A O P E N U N I V E R S I T Y
M.Sc. Botany, Part-II
PAPER-XI
(Molecular Biology)
Annual Examination, 2016
Time: 3 Hours. Full Marks: 80
Answer any Five Questions. All questions carry equal marks.
1. Describe mice experiment to prove that there is a method of transfer of genetic material in
Bacterium Pneumococcus.
2. Describe how packaging of DNA takes place in eukaryotes? What is the significance of
packaging of this DNA?
3. Explain in step-wise manner that Replication of DNA in Prokaryotes is semi-conservative.
Name the enzymes involved.
4. Write short notes on:
Nitrogenous bases
Significance of repair of DNA or Mismatch repair.
5. What are general properties of the genetic code? Explain wobble hypothesis.
6. Describe steps involved in the elongation of polypeptide during translation in prokaryotes.
7. What do you mean by splicing of RNA? Describe in detail the process of Pre-mRNA splicing.
8. Explain one gene one enzyme hypothesis.
9. Write short notes on any two of the following:
Pseudo genes Chargaff's rule
Selfish gene Split gene
10. Describe the concept of Prototrophs and Auxotrophs.