N A L A N D A O P E N U N I V E R S I T Y
M.Sc. Chemistry, Part-II
PAPER-XV
(Organic Synthesis)
Annual Examination, 2018
Time 3 Hours. Full Marks 80
Answer any FIVE Questions. All questions carry equal marks.
1. Discuss the preparation and four properties of thio-ether.
2. How organolithium compounds are prepared How does it react with unsaturated
ketone, Aryl halid, Alkyl-Arylether. In these reactions indicate the intermediate products
and mechanism involved.
3. Discuss reduction of alkynes i.e. hydrogenation by using any one of the following a
catalyst/reagent. Landler Catalysts, LiAlH4 .
Write the mechanism for the reduction of Cyclo-Pentanone with Sodium borohydride in water.
4. Discuss preparation, properties and use of sulphonal and mustard gas.
5. How are organomagnesium compound prepared How does Grignard reagent react with
Acetaldehyde Formaldehyde Acetone Carbondioxide
6. How sulphonic acid is prepared in Laboratory Give the reaction and mechanism. How does it
react with following when fused at 200-300°c Sodium hydroxide, Sodamide.
7. Write notes on the following Prevost Reaction Aldol reaction.
8. Elaborate the role of functional group interconversion in synthesis.
9. Write the mechanism of any two of the following
Claisen rearrangment Cope rearrangment Pinacol-Pinacolane rearrangment
10. What are Silanes How are they named Name the following compounds
3 HSi NH 2 2 CH 3 2 SiCl 2 C 2H 5 2 SiHOOCCH3
2H 5Si OH 3 H 3Si SiH 2 3 SiH 3