1
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI 600 034
M.Sc. DEGREE EXAMINATION BIOTECHNOLOGY
THIRD SEMESTER NOVEMBER 2017
BT 3824 NANOTECHNOLOGY MEDICAL BIOTECHNOLOGY
Date: 07-11-2017 Dept. No. Max. 100 Marks
Time: 09:00-12:00
PART A
Answer ALL the Questions
I. Choose the correct answer x 1 5 Marks)
1. The term Nanotechnology was coined by whom?
Richard Feynman Watson Crick Punnet
2. What is the size of double stranded DNA in mm?
3 b)2 1 4
3. What percentage of the population has Type I diabetes?
10 50 20 30
4. Amniocentesis can be performed at which trimester of pregnancy?
1st 2nd 3rd 2nd /3rd
5. Find out the negative regulator of P53 gene?
Mdm2 Mdm3 Mdm4 Mdm1
II. State whether the following are true or false. (5x1=5 Marks)
6. Ag Nanoparticles are less toxic, when compared to gold Nanoparticles.
7. TEM is used for measuring the size of nanoparticle.
8. 90% of the world population has type 2 diabetes.
9. ICM is obtained from blastocyst.
10. In situ hybridization is used for mapping gene on a chromosome.
III. Complete the following x 5 Marks)
11. Functional group in Nanoparticle can be measured by
12. Nanowires are used in Nanomedicine
13. Queen Victoria family is suffering from X linked recessive disorder.
14. of mother's blood has fetal DNA.
15. is a less severe form of DMD.
IV. Answer the following within 50 words x 1 5 Marks)
16. What is the use of TEM?
17. What is the contribution of Richard Feynman to Nanotechnology?
2
18. What is criss cross inheritance? Cite an example.
19. Define Amniocentesis
20. What is " Knudsun hypothesis " gene?
PART B
Answer the following each within 500 words. x 8 40 marks)
Draw diagrams wherever necessary
21. Discuss the use of DNA Nanomachine.
OR
Explain fullerenes in Nanotechnology.
22. Discuss the use of Nanotechnology in pollution control.
OR
Explain SEM.
23. How do you perform Multiplex PCR. Cite an example.
OR
Write an account on CFTR gene.
24. Explain DNA Fingerprinting.
OR
Explain Chorionic Villus Sampling (CVS).
25. Discuss the use of FACS.
. OR
(b)Explain In situ hybridization.
PART C
Answer any TWO of the following, each within 1500 words. x 20 40 Marks)
Draw diagrams wherever necessary.
26. Describe Carbon nanostructures.
27. Discuss type 2 diabetes, complication and its management.
28. Explain stem cell therapy.
29. Describe P53 gene and its role in cancer.