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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI 600 034
B.Sc. DEGREE EXAMINATION PHYSICS, CHEMISTRY, PLANT BIO.TECH.
FOURTH SEMESTER NOVEMBER 2016
AZ 4200 BIOINFORMATICS
Date: 11-11-2016 Dept. No. Max. 100 Marks
Time: 01:00-04:00
PART A [10 X 2 20]
ANSWER ALL THE QUESTIONS IN 50 WORDS EACH
1. Define Bioinformatics.
2. Name any four public domains.
3. How do you predict primary and secondary structure of protein?
4. Define homology modelling.
5. Distinguish analog and digital computers.
6. Name any four tools of genetic engineering.
7. Define Genetic Algorithm.
8. Compare primary and secondary structures of a protein.
9. Expand EMBL SQL.
10. State the role of BLAST and AUTODOCK.
PART B X 10
ANSWER ANY FOUR QUESTIONS IN 600 WORDS
11. How do you construct a phylogenetic tree using CLUSTAL-W?
12. Examine principle and applications of microarray
13. Examine the steps involved in DNA Southern blotting or fingerprinting
14. Depict an overview on network protocol, architecture, topology and wide area network.
15. What are biological data bases? How are they classified?
16. How do you compile and run a C-program?
PART C X 20
ANSWER ANY TWO QUESTIONS IN 1200 WORDS
17. Discuss the applications of bioinformatics
18. How do you perform computer aided drug designing using pharmacogenomics
19. What are the steps involved in DNA computing?
20. What are the events in post translational modifications of protein?