M.Sc. DEGREE EXAMINATION, NOVEMBER 2017
First Semester
Microbiology
Elective I — MOLECULAR BIOLOGY
(CBCS 2016 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 x 2 20)
Answer all questions.
1. Comment the genetic material function in the cell.
2. What are the different forms of DNA?
3. Explain the function of mRNA.
4. Define semi-conservative DNA replication.
5. What is the role of RNA polymerase?
6. Give role of nuzA protein.
7. Why genetic code is triplet?
8. What is the difference between a sense and non-sense
codon?
9. What is rasprotein?
10. What is an oncogenic virus?
Sub. Code
530501
RW-876
2
Ws5
Part B x 5 25)
Answer all questions, choosing either or
11. Write about structure and function of tRNA.
Or
Write a note on molecular basis of inheritance.
12. What is the function of topoisomerase in DNA
replication?
Or
What are the Okazaki fragments and why are they
needed?
13. Write a short note on Rho dependent and Rho
Independent termination.
Or
What is the role of general transcription factors and
where do they bind?
14. Explain about wobble hypothesis.
Or
Give a brief note on role of rRNA in protein
synthesis.
15. Explain briefly about the oncogenic proteins.
Or
Illustrate the viral transformation with suitable
example.
RW-876
3
Ws5
Part C 10 30)
Answer any three questions.
16. Discuss in detail about the structure forms, properties
and functions of DNA.
17. Write a detailed account on replication and enzymology of
DNA.
18. Give a detail comment about the transcription process in
prokaryotes.
19. Write a brief note on post translational modifications of
proteins.
20. Write a detailed note on structure, types and mechanism
of tumor viruses.
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