Exam Details

Subject pharmacogenomics
Paper
Exam / Course p.g. diploma in structural pharmacogenomics bioinformatics
Department
Organization alagappa university
Position
Exam Date December, 2017
City, State tamil nadu, karaikudi


Question Paper

P.G. DIPLOMA IN STRUCTURAL
PHARMACOGENOMICS EXAMINATION,
DECEMBER 2017
First Semester
Bioinformatics
PHARMACOGENOMICS
(CBCS 2013 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 x 2 20)
Answer all questions.
All questions carry equal marks.
1. What is Ayurgenomics?
2. Expand ADME.
3. Define microarray.
4. Write a few sentences on pharmacognosy.
5. What is TTD?
6. Write the importance of detoxification.
7. Comment on the Placebo-controlled clinical trial.
8. What is Haplo Chip?
9. Give a brief account on pharmacogenetics.
10. What is oligo microarray?
Sub. Code
510102
RW-1391
2
WSS
Part B x 5 25)
Answer all questions.
All questions carry equal marks.
11. Briefly discuss the concept of pharmacogenomics.
Or
Give a brief account on drug designing using
pharmacogenomics.
12. What is microsatellite? How is it useful in
identifying genetic variation?
Or
Write on structural changes due to polymorphism.
13. Give a brief account on detoxification of drugs.
Or
Briefly write the pharmacognosy in
pharmacogenomics.
14. Define ADME and its importance in drug designing.
Or
Write a brief account on lead identification.
15. Give a brief account on genome wide analysis of
alleles.
Or
Briefly describe the variation in human genome
with respect to alleles.
RW-1391
3
WSS
Part C x 10 30)
Answer any three questions.
16. Explain the therapeutic targets and gene based targets.
17. Write an essay on the role of polymorphism in developing
personalized medicine.
18. Discuss the metabolism of drugs and organic compounds.
19. Give a detailed account on the structural
pharmacogenomics.
20. Discuss the role of pharmacogenomics in the discovery of
anticoagulation drugs.
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Other Question Papers

Subjects

  • elective – i — immunoinformatics
  • lab i : computer aided drug designing (theory)
  • lab ii : structural biology (theory)
  • molecular cell biology and genetic engineering
  • molecular modeling and drug designing
  • pharmacogenomics
  • small and macromolecular x-ray crystallography