M.Sc. DEGREE EXAMINATION, NOVEMBER 2017
Bioinformatics
INTRODUCTION TO BIOINFORMATICS
(Common for M.Sc. (Bioinformatics), M.Sc. (Zoology),
M.Sc. (Microbiology))
(CBCS 2016 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 x 2 20)
Answer all questions.
1. Define Biological System.
2. How to create a directory in Unix OS?
3. Brief about "BLAST".
4. What can be inferred from sequence alignment?
5. Mention any two protein data bases.
6. Expand CSD and WDI.
7. How a genome database is arranged?
8. What are fragment libraries?
9. Mention two major infections and two non-infections
diseases among Indian population.
10. What are Telemedicines?
Sub. Code
502101/
509702/
530701
RW-843
2
WSS
Part B x 5 25)
Answer all questions, choosing either or
11. Discuss and appreciate the open sources in
bioinformatics.
Or
What is the different between windows and linux
operatives system?
12. Explain similarity, identify and conserved residues.
Or
Discuss any one algorithm for sequence alignment.
13. Appreciate Entrez system for information retrieval.
Or
Describe different structural databases.
14. Explain how chembank is organized.
Or
Describe SMILES and SMARTS notations.
15. Discuss about medical transcription.
Or
Appreciate the usefulness of Health Data
Management.
Part C x 10 30)
Answer any three questions.
16. Compare different operating systems for effective bioinfo
applications.
17. Relate various sequence alignment methods, strategies
and protocols.
RW-843
3
WSS
18. Justify the need to understand drug-drug interactions
and describe how to analyze the same.
19. How difficult it will be if chemical data bases are not
available for life science research.
20. Describe medical coding telemedicine and telehealth.
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