T.Y. B.Pharmacy Sem.) EXAMINATION, 2018
INDUSTRIAL PHARMACY—I
(2015 PATTERN)
Time Three Hours Maximum Marks 60
N.B. All questions are compulsory.
(ii Answers to the two sections should be written in separate
books.
(iii Figures to the right indicate full marks.
Neat diagrams must be drawn wherever necessary.
SECTION I
1. Attempt any one question
Explain in detail IP 2010 evaluation tests for tablets along
with specifications.
What is Pelletization Describe in detail steps involved in
extrusion spheronization.
2. Solve any four
Give classification of tablet.
Give construction and working of high speed mixer granulator
with diagram.
Explain process of fluid bed coating.
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Explain Rumpf classification.
What is the need for granulation.
Explain different stages in tablet formation.
Explain in brief mechanism involved in tablet disintegration.
3. Solve any two
Describe biopharmaceutical principles of dosage form design.
Give an account of different approaches to formulation of mouth
dissolving tablets.
Describe tablet friability apparatus and procedure to measure
friability.
Discuss schedule M guidelines for tablet manufacturing.
SECTION II
4. Answer the following (any one)
What is the purpose of tablet coating Discuss the common
defects associated with coated tablets and some likely causes
and the remedies thereof.
Enlist various materials used in capsule shell manufacturing.
Discuss in detail the process of manufacturing and quality control
of gelatin used in the capsule shell.
5. Solve any four
Explain weight variation test of soft gelatin capsules.
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