S.Y. B. PHARMACY (III Semester) EXAMINATION, 2018
PHARMACEUTICAL BIOCHEMISTRY
(2015 PATTERN)
Time Three Hours Maximum Marks 60
N.B. All questions are compulsory.
(ii Answers to the two sections should be written in separate
answer-books.
(iii Neat diagrams must be drawn wherever necessary.
Figures to the right side indicate full marks.
SECTION I
1. Explain effect of substrate concentration on anzyme activity. Discuss
Km and Vmax. 10
Or
Explain DNA Replication in Eukaryotic Cell.
2. Attempt short notes on any four of the following 12
Biological role of hyaluronic acid and heparin
Colour reactions of proteins
Genetic code of Eukaryotic cell
Classification of Lipids
Applications of enzymes with emphasis on marker enzymes
End Group analysis
Biological role of any three important amino acids.
P.T.O.
[5345]-3003 2
3. Write notes on any two of the following 8
Fibrous proteins
Secondary structure of proteins
Scope of Pharmaceutical Biochemistry in Pharmaceutical Sciences
Essential Fatty Acids.
SECTION II
4. Explain the steps involved in both phases of HMp shunt. Give the
significance of this metabolic pathway. 10
Or
Explain beta oxidation of unsaturated fatty acid. How are fats a
better fuel than carbohydrates
5. Attempt short notes on any four of the following 12
Ketone bodies
Deamination of Amino Acids
Oxidative phosphorylation
Vitamin K
Biosynthesis of Amino Acids
Glycerol metabolism
Glycogenolysis.
6. Write notes on any two of the following 8
Cholesterol synthesis and utilization
Pyrimidine biosynthesis
Urea cycle and its significance
Gluconeogenesis.