M.Sc. (Semester (CBCS) Examination Mar/Apr-2018
Biotechnology
CONCEPT OF BIOCHEMISTRY
Time: 2½ Hours
Max. Marks: 70
Instructions: Section- I is compulsory. Answer any four questions from Section-II.
Section I
Q.1

Multiple Choice Questions:
07
The pleated sheets in secondary structure of protein are stabilized by bonding between beta strands.
peptide
disulfide
glycosidic
hydrogen
A thermodynamic reaction can occur spontaneously only if the ΔG is
positive
constant
negative
maximum
In Ramchandran plot, the angles represent the bond angles in C-N bond.
psi
phi
gamma
delta
In Gauchers disease which is a genetic disorder, there is accumulation of in organs and tissues.
cerebroside
glucocerebroside
corticosteroid
dopamine
In Calvin cycle the Rubisco enzyme condenses CO2 molecule with to produce 3 phosphoglycerate.
Ribose 5 phosphate
Ribulose 5 phosphate
Ribose 1,5 bisphosphate
Ribulose 1,5 bisphosphate
Synthesis of fructose 2,6 bisphosphate from fructose 6 phosphate which stimulates glycolysis is catalyzed by
Aldolase
PFK-1
PFK 2
Enolase
The precursor molecule for the synthesis of steroid hormones and bile salts is
Acetyl COA
Cholesterol
Squalene
Glycogen

Define the following terms:
07
Gluconeogenesis
Metabolism
Secondary messenger
Entropy
Protein energy malnutrition
Protein stability
Cytokinins
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SLR-UE-85
Section II
Q.2
Add a detail account on 'Inborn errors of metabolism'.
14
Q.3
Add a detail account on glycogen metabolism.
14
Q.4
Give the general classification of hormones. Explain in detail the mechanism of action of any one hormone.
14
Q.5
Answer any Two of the following:
14
Explain structure and role of cAMP.
Describe hormonal control of pregnancy and lactation.
Describe the structural levels in protein. Add a note 'Ramchandran Plot'.
Q.6
Answer any Two of following:
14
Describe diabetis as a metabolic disorder
Describe Z Scheme of noncyclic phosphorylation.
Describe the laws of thermodynamics. Explain the concept of 'free energy'.