NOVEMBER 2018 Sub.Code :5055
M.B.B.S. DEGREE EXAMINATION
FIRST YEAR
PAPER V BIOCHEMISTRY I
Q.P. Code: 525055
Time: Three hours Maximum 50 Marks
Answer All Questions
I. Essay: x 10 10)
1. What is the normal blood glucose level? Discuss the factors regulating blood
glucose in the fasting and postprandial states. Write the diagnostic criteria for
diabetes mellitus.
II. Write notes on: x 4 20)
1. Classify membrane transport mechanisms. Add a note on active transport.
2. Fatty liver.
3. Types of enzyme inhibition with suitable examples.
4. Functions of vitamin B6 and its deficiency manifestations.
5. Biochemical changes in Atherosclerosis.
III. Short answers on: (10 x 2 20)
1. What are metalloenzymes? Give two examples.
2. What is glycemic index? Mention two examples of high glycemic index food.
3. Limiting aminoacids with examples.
4. Mechanism of action of methotrexate and dicoumarol.
5. Fluorosis.
6. Hemochromatosis.
7. Serum lipid profile.
8. Refsum's disease.
9. Essential pentosuria.
10. Lecithin sphingomyelin ratio.