M.Sc. (Semester (CBCS) Examination Nov/Dec-2018
Genetics
CELLULAR AND MOLECULAR BIOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Figures to the right indicate full marks.
Draw neat and labeled diagrams.
Q.1 Rewrite the sentences by choosing correct answer from given alternatives: 14
An energy does not required for
Facilitated diffusion Osmosis
Active transport Passive transport
RNA polymerase I is located in
Cytoplasm Nucleus
Nucleolus Mitochondria
SH2 domains specifically bind to
Phophoryleted serine residues Phosphoryled tyrosine residues
GDP Ca2+
-amanitin inhibits the action of
RNA polymerase I RNA polymerase II
RNA polymerase III DNA
of the following is not a type of signaling molecule.
Testosterone Insulin
Thyroxin Adenylatecyclase
refers to a messenger RNA which encodes SINGLE proteins.
MonocistronicMrna polycistronic mRNA
unicistronic mRNA polyreconic mRNA
Clathrin coated pits are associated with
phagocytosis pinocytosis
receptor mediated endocytosis exocytosis
receptor is a twelve pass transmembrane reseptor.
hedgehog G protein
patched disheveled
Degeneration of genetic code is attributed to the
1st member of codon 2nd member of codon
entire codon 3rd member of codon
10) cellorganell is known as sorting unit of cell.
Nucleus Golgi apparatus
Endoplasmic reticulum Mitochondria
11) Direct cell-cell transfer of ions take place through
Gap junctions Tight junctions
cadherins Integrins
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SLR-VK-310
12) enzyme is also known as Kornberg enzyme.
RNA polymerase DNA polymerase I
DNA polymerase II DNA ligase
13) In cell membrane, the carbohydrates in glycoprotein's or glycolipids are
oriented towards
outside inside
inside and outside randomly distributed
14) RNAi stands for
RNA interference RNA inducer
RNA insertion RNA nitron
Q.2 Answer the following any four:-
Replicon
Ribozymes
Selectins
Osmosis
Translation
08
Answer the following Any
Write a note on Hemidesmosomes.
Explain the structure of ER.
Give an account on NfKb pathway.
06
Q.3 Answer the following Any
Explain in detail initiation of DNA replication in Prokaryotes.
Write an account cell-cell interacting proteins.
Explain structure and function of RNA polymerase in prokaryotes.
08
Answer the following any
Explain GPCR pathway.
Explain transcription in eukaryotes.
06
Q.4 Answer the following Any
Write an account of Active transport.
Explain in detail mi RNA and its applications.
Explain genetic code and its properties.
10
Answer the following any
Explain components of plasma membrane.
Write an account on cell-matrix interaction.
04
Q.5 Answer the following. (Any two) 14
Explain Hedgehog signaling pathway.
Explain the mode of DNA replication.
Explain Movement of molecule across cell membrane.