M.Sc. (Semester (CBCS) Examination Nov/Dec-2018
Genetics
BIOSTATISTICS AND POPULATION GENETICS
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Draw neat and labeled diagram wherever necessary.
Figures to the right indicate full marks.
Q.1 Select correct alternatives for the following. 14
regarded as father of biostatistics.
Francis Galton Fischer
Karl Pearson Francis Bacon
The median of a series of numerical values is
A frequency table A number
A graph Equal to the average
The stages of the malignant cancer is recorded using the symbols II, III,
IV the scale used in it is
Normal Numerical
Ordinal Alphanumeric
Number which occurs most frequently in a set of numbers is
Mean Median
Skewness Mode
Frequency distribution whose most values are dispersed to left or right of
mode is classified as
Skewed Unimodal
Bimodal Explored
Difference of mode and mean is equal to
2(Mean-Median) 3(Mean-Median)
3(Mean-Mode) 2Mode-Mean
is not a central tendency.
Percentile Quartile
Standard Deviation Mode
Natural selection is best defined as occurring when the environment causes

Differential success in reproduction
Differential mortality
Assertive mating
A reduced gene pool
All alleles originate from
Mutations Cross over
Gene flow Non disjunction
10) The unit of evaluation is
Individual Species
Population Social group
Page 2 of 3
SLR-VK-308
11) When subpopulations are geographically isolated from each other process
is known as
Allopatric speciation Post mating isolations
Speciation Premating isolations
12) In brief periods of changes interrupt long period of stasis process is called
as
Speciation Mutation pressure
Punctuated equilibrium model Genetic pressure
13) QTL analysis is used to identify
Identify RNA polymerase binding sites
Map genes in bacterial viruses
Determine which genes are expressed at development stage
Identify chromosome regions associated with a complex trait in genetic
cross.
14) of the following statement about heritability are true.
Is a measure of level of gene linkage
Is a measure of inbreeding
Is a measure of level of heterozygotes in population
Is a measure of proportion of variation that is due to genetic causes
Q.2 Attempt any four of the following questions. 08
Define Statistics and Biostatistics
Define population and give its type
Define discrete variables
Define single-marker analysis
Define Co-adapted gene complex
Write a notes on. (Any Two) 06
Define graphical representation and enlist its advantages.
Explain Premating isolation.
Explain Traits controlled by two loci, three loci and multi-loci.
Q.3 Answer any two of the following questions. 08
Define frequency distribution with its type.
Explain concepts of species, Species types and Species categories.
Explain linkage map construction and single-marker analysis.
Answer any one of the following questions. 06
Explain applications and uses of biostatistics.
Explain Population Genetics, Birth of Neo-Darwinism and Genetics
polymorphism.
Q.4 Answer any two of the following questions. 10
Explain various parts of table.
Explain forces affecting the Hardy-Weinberg Genetic equilibrium.
Explain Heritability and measurement of variability.
Answer any one of the following questions. 04
Find out the median from following number
21 12 49 37 88 46 55 74 63
Muller's view, Dobzhansky view for origin of reproduction.
Page 3 of 3
SLR-VK-308
Q.5 Answer any two of the following questions. 14
Calculate the mean from the following data.
Class
Interval
10-20 20-30 30-40 40-50 50-60 60-70 70-80 80-90 90-100
Frequency 2 7 17 29 29 10 3 2 1
Calculate standard deviation from the following data of profits of companies.
Profits
(Rs. In Lacs)
20-30 30-40 40-50 50-60 60-70 70-80 80-90 90-100
Companies 30 58 62 85 112 70 57 26
Explain QTL mapping strategies.