B.Sc. II (Semester III) (Biotechnology) (Old CGPA)
Examination, 2018
IMMUNOLOGY II
Day and Date Wednesday, 2-5-2018 Max. Marks 70
Time 2.30 p.m. to 5.00 p.m.
N.B. All questions are compulsory.
Figures to the right indicate full marks.
Draw neat labelled diagrams wherever necessary.
1. Rewrite the sentences by selecting correct answer from the given alternatives 14
Secondary immune response is characterised by the production of
type of antibodies.
IgM IgG IgD IgE
ii) antibody is called as secretary antibody.
IgG IgM IgA IgE
iii) Blood group antigens are the examples of antigens.
Histocompatibility Auto
Iso Heterophile
iv) Antibodies labelled with enzyme are used in test.
Immunofluorescence Agglutination
Complement fixation ELISA
Class II MHC molecules peptide binding cleft is formed by domains.
α1 and α2 α1 and β1 α3 and β2 α2 and β2
vi)
cells are known as
THelper Dendritic cells
Tcytotoxic Macrophages
vii) test is used in diagnosis of enteric fever.
Tuberculin Widal VDRL Montoux
viii) Viral multiplication in animal cell is prevented by
Lysozyme Interferon
Colicin None of these
ix) B cells mature in
Lymph node Spleen Bone marrow Macrophages
In complement fixation test amboceptor is
Rabbit RBCs Anti-sheep RBCs
Horse RBCs Human RBCs
xi) VDRL test is used for diagnosis of disease.
Influenza Syphilis AIDs Typhoid
xii) refers to the ability of one cytokine having multiple effects
on diverse cell types.
Redundancy Synergy
Antagonism Pleiotropism
xiii) Endogenous antigen targeted for lysis first combine with small
protein molecule.
Calnexin Tapasin
Ubiquitin None of these
xiv) In alternate pathway binding of stabilizes the C3bBb.
Lectin Serine protease
Properdin C1
2. Answer any seven of the following 14
Define Hematopoiesis and give factors involved in hematopoiesis.
ii) Give primary and secondary lymphoid organs.
iii) Define agglutination and precipitation.
iv) Define antigen and give its type.
Give properties of cytokines.
vi) Define apoptosis and programmed cell death.
vii) Define ELISA and Immunofluorescence test.
viii) Define cross-reactivity and give its example.
Set P
SLR-SA 33
3. Answer any two of the following 10
Write an account on Lectin pathway.
ii) Write note on MHC class II molecule.
iii) Write note on factors affecting antigenicity.
Give an account on complement fixation test and Radioimmunoassay. 4
4. Answer any two of the following 14
Give basic structure antibody molecule and its different types.
ii) Give an account on processing and presentation of exogenous antigen.
iii) Classical complement pathway.
5. Answer any two of the following 14
Write an account on process of hematopoiesis.
ii) Immunodiffusion and Immunoelectrophoresis.
iii) Write note on cells of immune system.