B.Sc. III (Semester VI) (CGPA) Examination, 2018
Biotechnology
Applications
Day and Date Wednesday, 31-10-2018 Max. Marks 70
Time 10.30 a.m. to 1.00 p.m.
Instructions All questions are compulsory.
Figures to the right indicate full marks.
Draw neat and labeled diagrams.
1. Rewrite the following sentences by choosing correct alternatives. 14
50% Biomass of our planet is represented by
Microbes Plants
Animals Insects
The composition of oligonucleotide includes a single mixed oligonucleotides with ribonucleotides and deoxyribonucleotides.
Chimeric Antisense
Fused Antagonist
Subunit vaccine for cholera is prepared by epitope.
Cholera toxin A subunit Cholera toxin B subunit
Cholera toxin D subunit Cholera toxin C subunit
Halogenated aromatic compounds mainly present in pesticides and herbicides are converted to
Pyruvic acid Catechol
Protocatecol Succinic acid
A1 peptide domain of A subunit of has a toxic activity.
S. typhi Shigella V. cholerae P. vivax
Human growth hormone has amino acids.
100 121 191 181
is related with respiratory system.
Malaria Phenylketonuria
Anemia Cystic fibrosis
of the following has flat/irregular crystal shape.
CRI I (subgroup) CRY II (subgroup)
CRY IV CRY III (subgroup)
Phosphoramidate antisense oligonucleotides have been shown to be in vivo in mice.
Effective Inactive Neutral Toxic
10) compounds are chemicals which are foreign to the biosphere.
Xenobiotic Transgenic Gaseous Fluid
11) is the second generation of rDNA technology.
Metallergy Protein engineering
Engineering Lipid engineering
12) Genetically engineered X. Campestris was grow on whey due to insertion of gene.
Bacillus lac ZY E. coli lac ZY
Fungus lac ZY Pseudomonas lac ZY
13) Monellin is a which is 3000 times sweeter than sucrose.
Aldehyde Lipid
Protein Amino acid
14) is a infectious agent from HSV1 which elicit the antibodies that react against intact form of infectious agent.
Envelope glycoprotein A Envelope glycoprotein C
Envelope glycoprotein D Envelope glycoprotein B
2. Answer the following (any seven) 14
Explain in brief peptide vaccines.
Write a note on increase in enzyme stability.
Explain attenuated vaccine.
Explain antisense oligonucleotide.
Explain in brief synthesis of human growth hormone.
Enlist the applications of transgenic animals.
Write a note on gene therapy for cystic fibrosis.
Write a note on increase in activity of enzyme.
Write a note on interfering RNA.
3. Answer the following (any two) 10
Explain antisense RNA as therapeutic agent.
Explain cloning livestock by nuclear transfer.
Write a note on edible vaccines.
Explain synthesis of human interferon. 4
4. Answer the following (any two) 14
Discuss salt stress tolerant plants.
Give details of commercial production of fructose and alcohol.
Discuss vector vaccines directed against viruses.
5. Answer the following (any two) 14
Describe in detail transgenic mice.
How will you engineered a xanthomonas for xanthan gum production.
Explain development of senescence tolerant plants.